Oxytocin: physiological and pathophysiological determinants. A review
- Authors: Prokhorova O.V.1, Olina A.A.2,3,4, Tolibova G.K.2,3, Tral T.G.2,5
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Affiliations:
- Ural State Medical University
- The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- North-Western State Medical University named after I.I. Mechnikov
- Perm State Medical University named after Academician E.A. Wagner
- Saint Petersburg State Pediatric Medical University
- Issue: Vol 70, No 6 (2021)
- Pages: 105-116
- Section: Reviews
- Submitted: 21.03.2021
- Accepted: 22.10.2021
- Published: 15.12.2021
- URL: https://journals.eco-vector.com/jowd/article/view/63825
- DOI: https://doi.org/10.17816/JOWD63825
- ID: 63825
Cite item
Abstract
Oxytocin is a pleiotropic peptide hormone that plays a leading role in the implementation of the tonomotor activity of the myometrium during labor. Over the past decade, significant progress has been made in understanding the complex neurobiology of the oxytocin system, including oxytocinergic pathways, local release patterns and distribution of oxytocin receptors in the brain, and intra-neuronal oxytocin receptor signaling. This article presents the view of modern researchers on the biological functions of the hormone, including its participation in onco- and immunogenesis, as well as in the implementation of adaptation, reproduction and social behavior in humans.
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About the authors
Olga V. Prokhorova
Ural State Medical University
Author for correspondence.
Email: prokhorova-ov@yandex.ru
ORCID iD: 0000-0002-9051-4528
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, EkaterinburgAnna A. Olina
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; North-Western State Medical University named after I.I. Mechnikov; Perm State Medical University named after Academician E.A. Wagner
Email: olina29@mail.ru
ORCID iD: 0000-0001-9101-7569
SPIN-code: 4255-4325
Scopus Author ID: 56021173500
ResearcherId: T-8423-2017
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint Petersburg; Saint Petersburg; PermGulrukhsor Kh. Tolibova
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; North-Western State Medical University named after I.I. Mechnikov
Email: gulyatolibova@yandex.ru
ORCID iD: 0000-0002-6216-6220
SPIN-code: 7544-4825
Scopus Author ID: 23111355700
ResearcherId: Y-6671-2018
MD, Dr. Sci. (Med.)
Russian Federation, Saint PetersburgTatyana G. Tral
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott; Saint Petersburg State Pediatric Medical University
Email: ttg.tral@yandex.ru
ORCID iD: 0000-0001-8948-4811
SPIN-code: 1244-9631
Scopus Author ID: 37666260400
MD, Cand. Sci. (Med.)
Russian Federation, Saint PetersburgReferences
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