The potential of micronutrient support with omega-3 and omega-6 fatty acids in the prevention of human reproductive disorders

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Abstract

Omega-3 and omega-6 polyunsaturated fatty acids are among the nutrients essential for the vital functions of the human body. Fundamental cellular functions of omega-3 and omega-6 polyunsaturated fatty acids affect both physical and reproductive health. Based on the principles of personalized medicine, early detection of polyunsaturated fatty acid deficiency is necessary for its prompt correction and prevention of further diseases. We present a literature review on the effects of polyunsaturated fatty acids on female and male fertility. The brief information on biochemical aspects, current data on diagnosis, and possible methods for correction of polyunsaturated fatty acid deficiency are described in this article.

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About the authors

Tatyana S. Zhernakova

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Author for correspondence.
Email: tatazhernakova@gmail.com
Russian Federation, Saint Petersburg

Olesya N. Bespalova

The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott

Email: shiggerra@mail.ru
ORCID iD: 0000-0002-6542-5953
SPIN-code: 4732-8089
ResearcherId: D-3880-2018

MD, Dr. Sci. (Med.)

Russian Federation, Saint Petersburg

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Supplementary files

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2. Fig. 1. Features of the molecular structure of ω-3 and ω-6 PUFAs

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3. Fig. 2. Synthesis of ω-3 and ω-6 PUFAs. ARA cascade. Competitive synthesis of eicosanoids from ω-3 and ω-6 PUFAs for the same enzymes (delta-6-desaturase, lipoxygenase, and cyclooxygenase). EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid

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4. Fig. 3. Risk of developing age-associated diseases. EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 66759 от 08.08.2016 г. 
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия Эл № 77 - 6389 от 15.07.2002 г.


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