Surgical correction of the urethra in women with postcoital cystitis

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Abstract

AIM: The aim of this study was to improve the results of surgical treatment of patients with postcoital recurrent cystitis.

MATERIALS AND METHODS: From 2005 to 2021, in our clinic, extravaginal urethral transposition according to the method developed by us (RU No. 2408296 10.01.2011) was performed in 438 women aged 18 to 61 years (24 ± 1.3 years). The examination involved taking the anamnesis, physical examination, examination of the genitals, evaluation of urinalysis and urine culture, and bladder ultrasound.

RESULTS: Out of 438 women we operated on, 315 (71.9%) patients were examined in the long-term postoperative period. 297 (94.3%) patients had a positive result. Of these, 230 women had a full recovery and in 67 patients, cystitis occurs once or twice a year and is not always associated with intercourse. In 18 (5.7%) patients, the operation was ineffective, of which seven patients had exacerbations of cystitis after intercourse three years after the operation, and eleven patients had a reverse displacement of the urethra and the resumption of episodes of cystitis within a year after it. The repeated operation was performed in eight patients, it being effective in seven of them.

CONCLUSIONS: The new method of extravaginal transposition of the urethra according to Komyakov allows for avoiding the disadvantages of previously used operations. The main indication for the intervention is the direct relationship of cystitis episodes with sexual intercourse. The best results may be achieved with the correct selection of patients and compliance with all the technical features of the operation developed in our clinic.

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About the authors

Boris K. Komyakov

City Multidisciplinary Hospital No. 2; North-Western State Medical University named after I.I. Mechnikov

Email: komyakovbk@mail.ru
ORCID iD: 0000-0002-8606-9791
Scopus Author ID: 6507818933

MD, Dr. Sci. (Med.), Professor

Russian Federation, Saint Petersburg; 41, Kirochnaya St., Saint Petersburg, 191015

Vladimir A. Tarasov

City Multidisciplinary Hospital No. 2; North-Western State Medical University named after I.I. Mechnikov

Author for correspondence.
Email: vtar.sh@gmail.com
ORCID iD: 0000-0002-0196-849X

MD, Post-graduate of Urology chair

Russian Federation, Saint Petersburg; 41, Kirochnaya St., Saint Petersburg, 191015

Evgeny S. Shpilenya

City Multidisciplinary Hospital No. 2; North-Western State Medical University named after I.I. Mechnikov

Email: shpilenyaes@szgmu.ru
ORCID iD: 0000-0003-0479-6555

MD, Dr. Sci. (Med.), Professor

Russian Federation, Saint Petersburg; 41, Kirochnaya St., Saint Petersburg, 191015

Maxim V. Shevnin

City Multidisciplinary Hospital No. 2; North-Western State Medical University named after I.I. Mechnikov

Email: maxshevnin@mail.ru
ORCID iD: 0000-0002-5788-464X
Scopus Author ID: 57216661514

MD

Russian Federation, Saint Petersburg; 41, Kirochnaya St., Saint Petersburg, 191015

Igor V. Sinchenko

Academician I.P. Pavlov First Saint Petersburg State Medical University

Email: vtar.sh@gmail.com
ORCID iD: 0000-0003-4526-8943
Russian Federation, Saint Petersburg

References

  1. Gvozdev MJu, Loran OB, Gumin LM, D’jakov VV. Transpozicija distal’nogo otdela uretry v operativnom lechenii recidivirujushhej infekcii nizhnih mochevyvodjashhih putej u zhenshhin. Urologija. 2000;(3):29−32. (In Russ.)
  2. Komjakov BK. Jekstravaginal’naja transpozicija uretry v lechenii postkoital’nogo cistita. Urologija. 2013;(5):12−15. (In Russ.)
  3. O’Donnell RP. Relative hypospadias potentiated by inadequate rupture of the hymen: a cause of chronic inflammation of the lower part of the female urinary tract. J Int Coll Surg. 1959;32:374−388.
  4. Hirschhorn RC. Urethral-hymeneal fusion: a surgically correctable cause of recurrent cystitis. Obstet Gynecol. 1965;26(6):903−908.
  5. Van Bogaert LJ. Surgical repair of hypospadias in women with symptoms of urethral syndrome. J Urol. 1992;147(5):1263−1264. doi: 10.1016/s0022-5347(17)37536-5
  6. Derevjanko TI, Ryzhkov VV. Viral infections: human papillomavirus and genital herpes type 1 and type 2 as a cause of chronic recurrent cystitis with severe dysuria in women with urethral hypermobility and hypospadias. Urologija. 2015;(4):29−32. (In Russ.)
  7. Komjakov BK, Tarasov VA. Operativnaja korrekcija uretry pri postkoital’nom cistite. Urologija (Materialy XX kongressa Rossijskogo obshhestva urologv: bornik tezisov. 26-29 nojabrja, 2020). 2020;5(suppl.):283. (In Russ.)
  8. Sumerova N, Pushkar D, Gvozdev M. Transposition of distal urethra in female patients with recurrent lower UTI associated with sexual intercourse. In: Nikibakhsh A, ed. Clinical management of complicated urinary tract infection. 2011:218−224. doi: 10.5772/22301
  9. Nesterov SN, Rogachikov VV, Kisamedenov NG. Rekonstrukcija uretry v lechenii postkoital’nogo cistita. Jekologija i Medicina. 2009;(2):41−47. (In Russ.)
  10. Tarasov NI, Shul’gin AS, Nuriev AV. Diagnostika prichin i sovremennyj metod hirurgicheskogo lechenija postkoital’nogo cistita u zhenshhin. Nepreryvnoe medicinskoe obrazovanie i nauka. 2018;13(2):18−22. (In Russ.)
  11. Feofilov IV, Shkuratov SS, Pochivalov AK, et al. Jeffektivnost’ transpozicii uretry pri postkoital’nyh cistitah: pervye 15 operacij. Urologija. 2020;5(suppl.):295. (In Russ.)
  12. Komyakov B, Ochelenko V, Tarasov V. Surgical treatment of female urethra ectopia and hypermobility. Eur Urol. 2018;17(2 suppl):1668.
  13. Komyakov B, Ochelenko V, Tarasov V. Extravaginal transposition of urethra – the results of 412 operations. J Urol. 2020;203(4 suppl.):430–431.

Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 2. The final stage of the surgery. The urethral meatus was displaced and fixed in a new place and longitudinally sutured in its previous location

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3. Fig. 1. The surgery course: a — incision projections around the urethral meatus and its planned new location in the clitoris area; b — distal urethra mobilization; c — passage of the selected distal urethra through the formed tunnel to the site of its future location; d — additional urethral fixation with an interrupted suture when restoring the vaginal wall integrity

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4. Fig. 3. Dynamics of the number of operated patients

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