Adhesion prevention in reproductive surgery

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Abstract

Introduction. Adhesion formation in abdominal cavity is one of the leading disease. Adhesion formation after pelvic surgery is the cause of ileus, sterility and chronic pelvic pain. There is no foolproof method to prevent the adhesion constitution. There are some recommendations in the literature to prevent this process: to use crystalloids and colloids after basic operative stage, dosing irrigation the cavity with isotonic solution sodium chloride with heparin, administration of the glucocorticoid.

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Introduction. Adhesion formation in abdominal cavity is one of the leading disease. Adhesion formation after pelvic surgery is the cause of ileus, sterility and chronic pelvic pain. There is no foolproof method to prevent the adhesion constitution. There are some recommendations in the literature to prevent this process: to use crystalloids and colloids after basic operative stage, dosing irrigation the cavity with isotonic solution sodium chloride with heparin, administration of the glucocorticoid.

Design & Methods. The aim of our research is to make the protocol of application and valuation of adhesion barrier INTERCEED and gel INTERGEL effectiveness. The membrane INTERCEED was used after dissection of deep retrocervical endometriosis by laparoscopy in 11 patients, after myomectomy by laparoscopy in 35 cases, and in patients with sterility - in 18 cases. It’s known that these types of operations have the high risk of postoperative adhesion

constitution. INTERGEL was performed after laparoscopic adhesiolysis in 10 patients who had 2-4 open surgery before. We have done second-look laparoscopy in 34 cases after 4-6 months.

Results. Adhesion have been found in 6 cases but the intensive of adhesions was lower (number, quality, vascularisation etc.). 1 patient after 2 surgeries and laparoscopic adhesiolysis + INTERGEL was reoperated on 7-th day urgently (ileus). The gel and adhesion were not found.

There were 3 pregnant women after laparoscopic treatment of deep endometriosis + INTERCEED. There were 5 pregnancies after total laparoscopic adhesiolysis + INTERGEL in the patients with peritoneal infertility and 10 pregnancies after laparoscopic myomectomy.

Conclusion. Adhesion barrier is more important in the reproductive surgery. Now there are two kinds of barriers - membrane and gel. These data show the effectiveness and safety of both of them.

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About the authors

A. A. Popov

Dp. Endoscopy Moscow Reg. Research Institute

Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow

T. N. Manannikova

Dp. Endoscopy Moscow Reg. Research Institute

Email: info@eco-vector.com
Russian Federation, Moscow

О. G. Kirushkina

Dp. Endoscopy Moscow Reg. Research Institute

Email: info@eco-vector.com
Russian Federation, Moscow

N. А. Chausova

Dp. Endoscopy Moscow Reg. Research Institute

Email: info@eco-vector.com
Russian Federation, Moscow

Е. Yu. Gluchov

Dp. Endoscopy Moscow Reg. Research Institute

Email: info@eco-vector.com
Russian Federation, Moscow

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия Эл № 77 - 6389
от 15.07.2002 г.



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