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Background: genital prolaps which developes especially in young unipara women after noncomplicated delivery without hormonal disorders and factors provided intraabdominal pressure increasing is a common manifestation of generalized connective tissue defect (CTD) on the level of reproductive system. The Ist and IIId types of collagen define mechanical structure of ligaments. The immunohistochemical investigations in cases of CTD showed sufficient expression of the Ist and IIId types of collagen but they did not form typical dimensional structure and were replaced of IVth type of collagen that led to altered mechanical characteristics of ligaments.
Materials and methods. The method of surgery in patients with altered uterine fixation was aimed on liquidation of uterine prolapse and prevention of its further reccurence. The basic surgery - hysterectomy- was added of vaginopexy with prolen transplantant (Gyne Mesh or Gyne Mesh soft). At 13,5% of patients with CTD MESH - vaginopexy was performed as the basic surgery. Also vaginal hysterectomy, anterior vaginl plastics using synthetic materials, TVT or TVT-0 and other surgeries were made. 10 patients with CTD desired to save the reproductive function underwent nonradical surgery.
Results. The using of synthetic materials in patients with CTD is rational because of insufficiency of their own tissues, development of severe genital prolapse and high risk of reccurence.
About the authors
Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow
Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
Email: info@eco-vector.com
Russian Federation, Moscow
Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
Email: info@eco-vector.com
Russian Federation, Moscow
Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
Email: info@eco-vector.com
Russian Federation, Moscow
Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
Email: info@eco-vector.com
Russian Federation, Moscow
Moscow Regional Scientific Research Institute of Obstetrics and Gynecology
Email: info@eco-vector.com
Russian Federation, Moscow