Markers of connective tissue dysplasia in patients with chronic venouse insufficiency

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Introduction. Pelvic varicose is associated with different gynecologic diseases (myoma, ovarian tumors, endometriosis and others). Also it may be the independent disorder and cause chronic pelvic pain, sterility. The role of connective tissue disoders in varicose progressing is studed actively.

Objective: to evaluate markers of connective tissue displasia in female patients with pelvic varicose.

Materials and methods: The laporoscopy and physical exam were performed in 25 female patients (mean age range 32 ± 5,5 years) with symptoms of chronic pelvic pain. Physical examination was done to asses sixty five markers of connective tissue displasia by author's algorithm.

Results: Unilateral or bilateral varicose parametrial veins were found in all patients during laporoscopy. Nine patients (36%) had thinness or defects of uterine wide ligaments. Another diseases of reproductive system were not found. Twenty four patients (96%) had any markers of connective tissue displasia, such as migraine (91%), asthenic somatotype (74%), easy haemorrage formation (65%), vegetative disfunction (63%), constipation (55%), joint hypermobility (49%), thorax and spine deformation (36%), vaginal prolaps I - II (25%). Combination of 6-10 markers were found in 78% cases, 10-15 markers - in 22% cases. Any disembriogenesis stigms such as - the distorted little finger, epicantus, teeth anomaly, deformation of external ear, sandal shaped foot were found in 85% patients.

Conclusion: Markers of connective tissue system disorder were revealed in the most of patients with pelvic varicose. It is necessary take into account for risk groups formation and choice of treatment methods for patients with this disease.

About the authors

E. I. Rusina

Author for correspondence.
Email: info@eco-vector.com

Doctor of Medical Sciences

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