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Vol 50, No 4 (2001)

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Original Research

On the clinical significance of biovars ureaplasma urealyticum

Rishchuk S.V., Selkov S.A., Kostyuchek D.F., Vedeneeva G.N., Ivin D.I.

Abstract

Developing of chronic salpingoophoritis, non-specific bacterial vaginitis and specific candidamytotic vaginitis ought to be associated with complicated obstetric anamnesis and presence of biovar Parvo ureaplasmas predominantly found in women’s genital tracts. The correlation may be seen between identifying biovar Parvo ureaplasmas in men and arising of torpid and chronic infectious urethritis, that may testify to its more intensive pathogenic effect comparing with biovar T- 9GO. Detection of biovar T-960 in urogenital system in men and women doesn’t exclude the possibility of inflammation, that implies adequate complex therapy identical to that in case of biovar Parvo.

Journal of obstetrics and women's diseases. 2001;50(4):17-20
pages 17-20 views

Analysis of the severity of clinical manifestations of endometriosis in the long term after radical surgical treatment

Konovalov V.I., Vorontsova A.V.

Abstract

Comparative analysis of the endometriosis main clinical manifestations (pain syndrome in the small pelvic area, menstrual and generative functions disorders, adjacent organs dysfunction) has been carried out in 111 women in long-term period after efficient operative interventions and 371 women with endometriosis who didn’t get any treatment. None of the above-mentioned methods of the efficient surgical treatment turned to be optimal (long-term and effective) for cutting short the main clinical manifestations of endometriosis.

Journal of obstetrics and women's diseases. 2001;50(4):21-24
pages 21-24 views

Diagnostic role of uterine artery dopplerometry in the first trimester of pregnancy

Orlov V.I., Orlov A.V., Zamanskaya T.A., Podolskaya T.V.

Abstract

A Doppler sonographic examination of blood flow in the left and right uterine arteries was carried out in women in the first trimester of pregnancy. Systolic- diastolic ratio (S/D) andpulsative index (PI) were assessed in 71 women with physiological course of pregnancy and in 49 women with threatened abortion. The investigation revealed clear connection of the uterine blood flow lateralization and corpus luteum localization. These interrelations are characterized differently in case of physiological pregnancy and threatened abortion. The new approach to the evaluation of uterine blood flow gives an ability ofpreclinical diagnostics of threatened abortion.

Journal of obstetrics and women's diseases. 2001;50(4):25-28
pages 25-28 views

The use of the drug mildronate in obstetrics

Pavlova N.G., Krivtsova E.I., Konstantinova N.N.

Abstract

The report contains data on positive influence of mildronatum infusion (10% NaCl) on uterine-placental and fetoplacental circulation in women with chronic placental insufficiency in the third trimester of pregnancy.

Journal of obstetrics and women's diseases. 2001;50(4):29-33
pages 29-33 views

Positive experience in laser therapy of patients with polysystemic disorder syndrome with hvdmp using scanning beams through the vagina

Baranov V.N.

Abstract

Low-intensive laser therapy was carried out on 550 women aged 18 to 33 with syndrome of polysystemic disorders at chronic genital inflammations.
Efficiency of frequency movement (301 patients) and stable regime (249 patients) of endovaginal low-intensive laser therapy has been studied by means of complex clinical, functional, instrumental, and laboratory examinations. Movement regime of laser application proved to stimulate sexual visceral reactions improving the state of female organism in case of syndrome of polysystemic disorders. Normalization of the sexualfunction as a result of movement regime in endovaginal laser therapy can be considered as pathogenic influence directed on normalizing and supporting physiological nervous-reflex connections of genital organs with other organs and systems of women’s organisms.

Journal of obstetrics and women's diseases. 2001;50(4):34-37
pages 34-37 views

Clinical characteristics of patients with reproductive dysfunction and benign ovarian neoplasms

Gataulina R.G.

Abstract

The study reports on the analysis of the anamnestic data of2044 women with reproductive disorders who underwent operative interventions for tumors and tumor¬like masses of the ovaries during the period of 1989-1999 in the Research Center of Obstetrics, Gynecology and Perinatology of the Russian Academy of Medical Sciences. A high incidence rate о f complicated anamnesis and the coexisting somatic and extragenital diseases was revealed. The data are presented concerning the status of menstrual and reproductive function of the patients examined.

Journal of obstetrics and women's diseases. 2001;50(4):38-42
pages 38-42 views

Dyshormonal dysplasias of the mammary gland in adolescent girls

Kravchenko E.V.

Abstract

436 juvenile girls were examined. The results received indicate that dyshormonal dysplasia of mammary glands takes an important place in gynecologic morbidity of juvenile girls (11% of those who consulted a gynecologist). Diffuse forms that can be treated conservatively are mostly diagnosed. The main diagnostic methods in teenagers are palpation and MESUSS. Considering polyethiology of the disease, conservative therapy ought to be complex. To avoid carcinogenic effect of oral contraceptives, they may be used in case of non-complicated heredity, intact liver, and non-complicated course of perinatal period of the girl.

Journal of obstetrics and women's diseases. 2001;50(4):43-45
pages 43-45 views

Gynecological morbidity in girls and adolescent girls in a large industrial city

Khamadyanov U.R., Muslimova A.R.

Abstract

The results of randomized complex clinical andlaboratory examination of 1540 girls and juveniles are drawn, which characterize the rate and the structure of gynecological pathology under conditions of an industrial city. Gynecological morbidity proved to be closely associated with the state of somatic health in girls. Disorders of menstrualfunction occupy the most important place in the structure of gynecological pathology, dysfunctional uterine bleedings prevailing over other kinds of pathology. Anonymous questionnaire of 1700juveniles revealed some peculiarities of their reproductive and contraceptive behavior. The age of the beginning of sexual life at the average comes up to 14,6 ±0,5 years in the city of Ufa (an average age over Russia — 16,1 years), the rate of juveniles who use adequate contraceptives being very low (9,5%). The article gives light to the problems of elaborating the system of organizational and medico-prophy lactic measures for girls and juveniles with gynecological pathology andputtingthem into practice.

Journal of obstetrics and women's diseases. 2001;50(4):46-51
pages 46-51 views

Blood supply to the uterus and ovaries in healthy women and patients with ovarian insufficiency

Dzhemlikhanova L.X., Bogdanova M.N., Kogan I.Y.

Abstract

The aim of this study was to investigate the relation between ovarian blood flow, folliculogenesis and sex-steroid production during normal menstrual cycle and in women with ovarian failure. Ten healthy women and 40 patients with ovarian failure underwent hormonal assays (follicle-stimulating, luteinizing hormones, estradiol, progesterone, prolactine, testosterone) and ultrasound examination of the uterus and ovaries with color Doppler ultrasonography of the uterine and ovarian vessels on the 3 -5th, 11- 13th, 17- 19th and 21 -23rd days оf menstrual cycle. Intraovarian blood flow of the ovary carrying the predominant follicle in healthy women appeared more active than in conrdlateral ovary on the 3-5th days of the cycle. Inpatients with ovarian failure no difference was detected between the ovaries during the periods in question. Ovarian and uterine blood flow inpatients with the ovarian failure was less intensive comparingwith healthy women. Positive correlation between uterine blood flow and estradiol concentration in serum was revealed.

Journal of obstetrics and women's diseases. 2001;50(4):52-57
pages 52-57 views

Features of functional maturation of the central nervous system in fetuses with multiple pregnancies

Prokhorova V.S., Pavlova N.G., Konstantinova N.N.

Abstract

The study was undertaken to detect some peculiarities of fetal «rest — activity» cycle formation in multiple pregnancy. 86 fetuses (43 twins) were observed with the following assessment of the newborns’neurological status. The «rest — activity» cycle parameters and haemodynamic indices of fetoplacental system were examined. Also there was considered the influence of IUGR and twins birth weight discordance on CNSfunctionalformation. The results showed that twins comparing with single pregnancies are characterized by the retardation of «rest — activity» cycle formation that is manifested in shortening оf the quite and prolongation оf the intermediate states, lowering of cardiac rhythm variability and motorcardial reflex. These findings substantiate the necessity of including twins into high-risk group concerning neurological disorders in the newborns. The IUGR appears an additional factor increasing this risk.

Journal of obstetrics and women's diseases. 2001;50(4):58-63
pages 58-63 views

Clinical experience of using the method of abdominal decompression in pregnant women

Repina M.A., Novikov B.N., Romanova L.A., Gaidukova I.R.

Abstract

An effective physiotherapeutic method of abdominal decompression was offered with the aim of treating miscarriage and fetoplacental insufficiency in pregnants. 37 women with the pathology in question, who were in the II or III trimester of pregnancy, were examined. The results of the investigation show that abdominal decompression may become an alternative to orthodox methods of treatment and it may be widely applied in obstetrics.

Journal of obstetrics and women's diseases. 2001;50(4):64-66
pages 64-66 views

17p-estradiol (1 mg daily) in continuous combination with dydrogesterone (5.10 or 20 mg daily) increases bone mineral density in postmenopausal women

Stevenson J.С., Teter P., Lees В.

Abstract

Although the minimal dose of 17/3-estradiol in hormone replacement regimens was originally considered to be 2 mg a day, it is now increasingly accepted that a lower dose of 1 mg a day is effective in protecting women from the detrimental effects of the menopause. A 1-year, multicentre, double-blind, randomized study was conducted in 214 healthy postmenopausal women in order to assess the effect of 17(3-estradiol (1 mg a day) continuously combined with dydrogesterone (5,10 or 20 mg/day) in preventing bone loss. Bone mineral density (BMD) was evaluable in 177 women who completed the study. In all women, a statistically significant increase from baseline in lumbar vertebrae (L.2~L4) BMD was seen after 6 months (+ 2,4%; p<0,01); this increase was somewhat greater after 12 months (+ 3,6%;p < 0,01). Similar effects were seen in the hip. After 6 months, BMD in the femoral neck, Ward’s triangle and trochanter had increased by 0,20% (not significant [n.s.]), 0,32% (n.s.)and 1,08% (p<0,01), respectively, compared with baseline. Greater increases were again seen after 12 months (+1,16%, + 1,62% and +2,83%, respectively), all of which were statistically significant (p<0,01) compared with baseline. The change in BMD from baseline did not diff er significantly between the three dydrogesterone dosages for either L.2~L4 or hip. All dosages were well tolerated and amenorrhoea was achieved in over 70%. In conclusion, 17(3-estradiol (1 mg/day) continuously combined with dydrogesterone (5, 10 or 20 mg/day) results in a significant increase in lumbar vertebrae and hip BMD in postmenopausal women. The lower dose of oestrogen and the avoidance of cyclical bleeding make this a particularly suitable regimen for the prevention and treatment of osteoporosis in older women.

Journal of obstetrics and women's diseases. 2001;50(4):67-71
pages 67-71 views

The effectiveness of the drug Divigel in patients with surgical menopause

Yureneva S.V.

Abstract

Twenty women with surgical menopause aged40-50years received parenteral hormonal replacement therapy with estradiol (preparation Divigel) for the period of 12 months. Twenty healthy women formed the control group. The following indeces were estimated during the study: menopausal Kupperman’s index, and the leveloffollicle-stimulatinghormone and estradiol in blood serum. Kupperman’s index remarkably decreased in the course of treatment (p<0,05). Decrease of FSH level was associated with stable growth of estradiol level (p<0,05). The absence of manifested side effects and considerable change of body build index, the possibility of choosingthe minimal effective doze individually allow to apply HRT with Divigel more widely.

Journal of obstetrics and women's diseases. 2001;50(4):72-73
pages 72-73 views

Experience in the use of cognitive psychocorrection of the emotional state of women with complicated pregnancy in the third trimester

Nesenchuk V.V., Serebryakova R.O., Arzhanova O.N.

Abstract

In the article the data of experimentalpsychological investigation of pregnant women with complicated course of gestation are drawn to determine the peculiarities of their psychological status. One hundred pregnant women in the third trimesterwere examined, 64 of them demonstrated symptoms of late gestosis. The investigation revealed high level of both reactive and personal anxiety in women with complicated course of pregnancy. All the women of this group were subjected to supporting psychotherapy, which was directed to the decreasing psychological troubles. The basic aim of cognitive psychocorrection was to overcome different systemic presuppositions, to help the pregnant women to elaborate an alternative behavioral pattern and to change their attitude to themselves, to form the sense of self-confidence. The results received testify to the expediency of including psychotherapy (supporting and cognitive psychocorrection) into the complex of treatment.

Journal of obstetrics and women's diseases. 2001;50(4):74-76
pages 74-76 views

Comparison of laboratory diagnostic methods for urogenital infections caused by Chlamydia trachomatis

Shalepo K.V., Shipitsina E.V., Savicheva A.M., Domeyka M.

Abstract

According to the Russian-Swedish project there was performed a comparison of methods used for Chlamydia trachomatis detection in cervical samples, obtained from 397women and urethral samples from 253 men. All specimens were examined by direct immunofluorescence (DIF), polymerase chain reaction (PCR) and cell culture (CC). In high-prevalence group (group I) chlamydiae were detected in 17,8% and 28,0% of cases in men and women, respectively. Ingroup II containing patients who were subjected to screening examination, chlamydiae were found in 5% of cases both in men and women. PCR was shown to be the most sensitive when cervical samples in group I and cervical and urethral samples in group II were investigated. When urethral samples in group I were tested, DIF proved to have the highest sensitivity. All the methods used were found to be high specific. The search for standards of genital chlamydial infection diagnosis is in progress.

Journal of obstetrics and women's diseases. 2001;50(4):77-82
pages 77-82 views

Oncological issues of hormonal contraception and hormone replacement therapy

Urmancheeva A.F., Kutusheva G.F.

Abstract

The article gives critical analysis of numerous epidemiological studies touching upon the problems of carcinogenesis while using hormonal contraception and hormonal replacement therapy and also the expediency of HRT as to oncologic patients after radical treatment.
The materials presented testify to relative carcinogenous safety of hormonal contraceptives as to the majority of tumors and even considerable decrease of endometrial and ovarian cancer risk; but some investigations point to the increase о f breast cancer in case о f prolonged application о f hormonal preparations.
The results оf the analysis show that HR Tmay be recommended among female population providing active screening, especially of mammary glands and endometrium. Besides that, hormonal preparations are not excluded for rehabilitation of some oncologic patients underthorough monitoring. Yet, there exists burning necessity of continuing cooperated scientific and clinical investigations forfurther studying oncologic aspects of hormonal contraception and HRT.

Journal of obstetrics and women's diseases. 2001;50(4):83-89
pages 83-89 views

Psychoemotional disorders in postmenopausal women and methods of their correction

Niauri D.A., Petrova N.N., Chanysheva O.G., Grobova O.V.

Abstract

Psycho-emotional disorders in postmenopausal women are caused by interaction of neuroendocrine changes, psychological and social factors. They include anxiety, depression, dissomnia,psychosexual and cognitive dysfunction. Hormonal replacement therapy is widely used in correction of psycho-emotional disturbances in postmenopausal women. Combination of estrogens and antidepressants appears to have good prospects.

Journal of obstetrics and women's diseases. 2001;50(4):90-95
pages 90-95 views

jubilee

Gennady Alexandrovich Savitskii

Abstract

The editorial board and editorial board of the Journal of Obstetrics and Women's Diseases congratulates Professor Gennady Aleksandrovich Savitsky, one of the brightest and most distinctive representatives of the St. Petersburg School of Obstetrics and Gynecologists, on his birthday. Most of the scientific and medical activities of Gennady Aleksandrovich take place within the walls of the N.N. D.O. Ott RAMS.

Journal of obstetrics and women's diseases. 2001;50(4):1-1
pages 1-1 views

Current public health problems

Hormonal contraception for women with type 1 diabetes

Ailamazyan E.K., Nikitin S.V., Potin V.V.

Abstract

The investigation demonstrates the influence ofperoral combined contraceptives and preparations containing only progestagens on carbohydrate and lipid exchange and haemostatic system. The factors, which exert influence upon metabolic indices in women with type I insular diabetes, are estimated. The correlation between the intake of combined and containing only progestagens contraceptive preparations and the risk of tromboembolism is revealed. The indications and contraindications are defined for the prescription of peroral contraceptives in women with type I insular diabetes.

Journal of obstetrics and women's diseases. 2001;50(4):8-13
pages 8-13 views

Hormonal, metabolic and clinical manifestations of the climacteric syndrome as a marker of ecological trouble in the region

Shutova I.A.

Abstract

In the early 90s, academician E.K. Ailamazyan formulated the main provisions of general ecological reproductive science and the concept arising from them, according to which indicators of the reproductive function of women can act as criteria for assessing the ecological situation in the region. In 1995, an employee of the Institute of Obstetrics and Gynecology. D.O. Ott.

Journal of obstetrics and women's diseases. 2001;50(4):14-16
pages 14-16 views

Viewpoint

Female military personnel in the navy - a paradox or a reality?

Tsutsiev S.A., Lizunov Y.V., Terentyev L.P., Tsutsieva M.G.

Abstract

The reorganization of the Armed Forces, which has been realized for the last decade, touched over the sexual structure of defenders of our Motherland: one can witness an increasing tendency of employing women on military service.
Legal equality of sexes doesn’t allow to avoid the differences between the man and the woman, which are genetically conditioned. One of the actual problems of the Army today is the task of providing optimal conditions of military service for women. The realization of this task depends first of all on principal position of the commanders of all levels. This implies the necessity of hygienic education of the commanders under the management of hygienists with the aim of radical change of their attitude to military women.

Journal of obstetrics and women's diseases. 2001;50(4):96-99
pages 96-99 views

Casuistry

Full-term abdominal pregnancy case

Orlov V.I., Estrin V.V., Shevko I.G., Rozina V.I., Sagamonova K.Y., Zinkin V.I.

Abstract

The article gives account of the case offull-term abdominal pregnancy with comparatively favourable course that led to diagnostic mistakes and complications, but resulted in the birth of healthy child without any signs of asphyxia.

Journal of obstetrics and women's diseases. 2001;50(4):100-101
pages 100-101 views

History page

To the 125th anniversary of the first defense in Russia by a woman of a dissertation for the degree of Doctor of Medicine

Tsvelev Y.V.

Abstract

Speaking about the lesser preparation of women for mental work, we do not want to express by this a hint of their inability for this work. On the contrary, we may be more than anyone else, would like to see it, would like full scope for female development and are sure that under the changed circumstances, the female mind will eventually become as receptive and productive as the male brain. If now more was opened up for a woman, or even any kind of application of mental forces in civil life, for example, if she could be a doctor, teacher, etc., then it goes without saying that along with the request, and these forces. V. M. Florinsky (1866)

Journal of obstetrics and women's diseases. 2001;50(4):102-105
pages 102-105 views

Некролог

Doctor, teacher and scientist (in memory of Professor Viktor Pavlovich Baskakov)

Tsvelev Y.V., Kira E.F.

Abstract

On November 11, 2001, at the age of 78, Doctor of Medical Sciences, Professor Viktor Pavlovich Baskakov, suddenly died. It is difficult to get used to the thought and hard to realize that there is no longer this life-loving person among us, a magnificent obstetrician-gynecologist, a prominent scientist and talented teacher.

Journal of obstetrics and women's diseases. 2001;50(4):110-111
pages 110-111 views


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