Humoral and mucosal immunity in uncomplicated and complicated EPH-gestos of pregnants
- Authors: Aleksandrova M.O.1,2, Tchebotkevitch V.N.1,2
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Affiliations:
- I.P. Pavlov State Medical University
- Institute of Hematology
- Issue: Vol 48, No 5S (1999)
- Pages: 27-27
- Section: Articles
- Submitted: 14.02.2022
- Accepted: 14.02.2022
- Published: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/100756
- DOI: https://doi.org/10.17816/JOWD100756
- ID: 100756
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Abstract
Objective: to study the humoral and mucosal immunity in uncomplicated and complicated EPH-gestos of pregnants.
Keywords
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Objective: to study the humoral and mucosal immunity in uncomplicated and complicated EPH-gestos of pregnants.
Method: 66 women with uncomplicated (n=20) and complicated with EPG-gestos (n=42) of pregnancy were studied. In serum and cervical mucosa samples the level of Ig A, Ig M, Ig G were controlled.
Results: the concentration of serum Ig G in uncomplicated cases was 10,2 + 0,6 g/l, whereas the level of mucosal Ig A, Ig M and Ig G was 0,25 + 0,06 g/l; 0,19 + 0,06 g/l; and 0,60 + 0,03 g/l comparatively. The statistically significant (p< 0,05) increase in the level of serum Ig M and mucosal Ig M was detected in complicated cases. The degree of this increase correlated with the severity of toxemia in pregnant women. The level of serum Ig G was lowest in edema cases, Ig G in mucosa was not detected at all, whereas mucosal Ig A was increased in 1,7 once more in comparison with healthy pregnants.
Conclusion: we conclude that the results reflect the disturbance in protein metabolism in EPG-gestos and on other hand demonstrate the relative activation of the mucosal immunity.
About the authors
M. O. Aleksandrova
I.P. Pavlov State Medical University; Institute of Hematology
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg
V. N. Tchebotkevitch
I.P. Pavlov State Medical University; Institute of Hematology
Email: info@eco-vector.com
Russian Federation, St. Petersburg; St. Petersburg