Placental insufficiency treatment in patients with herpes virus infection
- Authors: Tioutiounnik V.L.1, Ordzhonikidze N.V.1, Zaidieva Z.S.1, Kravchenko N.F.1
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Affiliations:
- Research Centre of Obstetrics, Gynecology & Perinatology
- Issue: Vol 48, No 5S (1999)
- Pages: 163-163
- Section: Articles
- Submitted: 23.02.2022
- Accepted: 23.02.2022
- Published: 15.12.1999
- URL: https://journals.eco-vector.com/jowd/article/view/101517
- DOI: https://doi.org/10.17816/JOWD101517
- ID: 101517
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Full Text
Abstract
Objective: To evaluate the efficacy of immunocorrective therapy in complex treatment of placental insufficiency in pregnant women with herpes virus infection (herpes simplex virus infection and cytomegalovirus).
Full Text
Objective: To evaluate the efficacy of immunocorrective therapy in complex treatment of placental insufficiency in pregnant women with herpes virus infection (herpes simplex virus infection and cytomegalovirus).
Methods: 77 cases with disease relapses and asymptomatic elimination of virus were examined.
Results: Discovered disorders in immune and interferon statuses allow to prescribe for these patients immunocorrective therapy. For this purpose, we have used intravenous injections of immunoglobulin (250 mg/kg) 3 times a day in I, II and III trimesters of pregnancy. We have also used rectal suppositories with viferon (which consist of 150 000 ME alpha-2b interferon) 2 times a day for 5 days since 28 to 34 weeks of gestation. Viferon suppositories consisted of 500 000 ME of alpha-2b interferon have been prescribed 2 times daily after 35 weeks of gestation. Totally, we use a 12 week course of weekly viferon.
Conclusions: It was found that this therapy leads to a firm normalization of immune and interferon status in pregnant women with herpes virus infection and improves the effect of complex treatment of placental deficiency in these patients.
About the authors
V. L. Tioutiounnik
Research Centre of Obstetrics, Gynecology & Perinatology
Author for correspondence.
Email: info@eco-vector.com
Russian Federation, Moscow
N. V. Ordzhonikidze
Research Centre of Obstetrics, Gynecology & Perinatology
Email: info@eco-vector.com
Russian Federation, Moscow
Z. S. Zaidieva
Research Centre of Obstetrics, Gynecology & Perinatology
Email: info@eco-vector.com
Russian Federation, Moscow
N. F. Kravchenko
Research Centre of Obstetrics, Gynecology & Perinatology
Email: info@eco-vector.com
Russian Federation, Moscow