Diffuse non-toxic goitre and femaile reproductive function

Аннотация

Objective and Methods. 150 women with diffuse non-toxic goitre (DNG) age 19-42 and 80 healthy women of the same age were examined with ultrasonic determination of thyroid volume, colpocytology, basic thermometry, serum levels of gonadotropins, prolactine, thyroid hormones, estradiol, progesterone by immunofermentic method.

Полный текст

Results. 31 women (20,6%) with DNG revealed such reproductive dysfunction as short hyperthermic menstrual phase, low excretion of estradiol and progesterone on the 20^th and 24^th days, anovulative luteinization in comparison with 9 women (11,2%) of control group (p<0,05).

Conclusions. These tests indicated an inadequate response mechanism between thyroid, hypothalamic and ovarian systems in patients with DNG.