Genital HPV - infection in women of reproductive age

详细

Objective. To reveal HPVs of high risk for the development of cervical carcinoma in women of reproductive age.

全文:

Methods. Clinical and microbiological methods were used. HPVs were studied by means of a Hybrid Capture II System.

Results. 309 women were examined. Oncogenic types of HPVs were found in 112 (36.2%) of them.

High risk HPVs were determined in all cases of cervical carcinoma in one of 5 cases of vulvovaginal carcinoma and in no case of ovarian cancer HPVs were revealed. In the presence ofpointed condyloma and papilloma in the genital area 17 (40.5%) out of 42 patients had high risk HPVs. Examination of 78 patients with cervical erosion and/or dysplasia has shown high risk HPV in 32 (41%) of them. HPVs were also found in cervical and ovarian inflammatory and noninflammatory diseases (endometritis, salpingitis, endometriosis) in 25 % of cases. 85% of women with high risk HPV had early beginning of sexual life and polygamous sexual behaviour (from 2 to 20 partners) and, as a consequence, various STDs in anamnesis.

Conclusions. The data obtained entirely correspond to the idea of belonging HPVs to the agents that are sexually transmitted. The determination of HPV markers allows to specify the contingent of women who need periodical examination.