Vaginal microbiota stability as a marker of successful outcomes of pregnancy
- Authors: Beliaeva N.R.1, Budilovskaya O.V.1, Savicheva A.M.1, Tapilskaya N.I.1, Kogan I.Y.1
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Affiliations:
- The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- Issue: Vol 72, No 4 (2023)
- Pages: 71-80
- Section: Reviews
- URL: https://journals.eco-vector.com/jowd/article/view/117519
- DOI: https://doi.org/10.17816/JOWD117519
- ID: 117519
Cite item
Abstract
Overcoming the problem of miscarriage still remains relevant today. Its' significant contribution to the structure of premature birth is due to the invasion of conditionally pathogenic microflora from the lower parts of the genital tract into the amniotic cavity. It can thus trigger an inflammatory reaction, causing early termination of pregnancy. The microbiota of the genital tract is characterized by the least diversity and high stability over time compared to any other location of the body. The dominance of certain types of lactobacilli in the vaginal biotope may be a marker of well-being, or a harbinger of termination of pregnancy. The aim of this review article is to summarize the current understanding of the vaginal microbiota during pregnancy in order to determine the relationship between its composition and stability throughout pregnancy, as well as the risk of early termination of pregnancy.
Full Text
About the authors
Natalia R. Beliaeva
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Author for correspondence.
Email: natascha778@yandex.ru
ORCID iD: 0000-0002-4277-1474
SPIN-code: 4126-3035
Russian Federation, Saint Petersburg
Olga V. Budilovskaya
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: o.budilovskaya@gmail.com
ORCID iD: 0000-0001-7673-6274
Scopus Author ID: 12545757500
ResearcherId: K-1854-2018
MD, Cand. Sci. (Med.)
Russian Federation, Saint PetersburgAlevtina M. Savicheva
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: savitcheva@mail.ru
ORCID iD: 0000-0003-3870-5930
SPIN-code: 8007-2630
ResearcherId: P-6788-2015
MD, Dr. Sci. (Med.), Professor, Honored Worker of Science of the Russian Federation
Russian Federation, Saint PetersburgNatalia I. Tapilskaya
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: tapnatalia@yandex.ru
ORCID iD: 0000-0001-5309-0087
Scopus Author ID: 23013489000
ResearcherId: A-7504-2016
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgIgor Yu. Kogan
The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: ikogan@mail.ru
ORCID iD: 0000-0002-7351-6900
SPIN-code: 6572-6450
Scopus Author ID: 56895765600
ResearcherId: P-4357-2017
MD, Dr. Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences
Russian Federation, Saint PetersburgReferences
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