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Representativity of macular edema mapping using en face optical coherence tomography, retinal thickness map, and fluorescein angiography
- Authors: Maltsev D.S.1, Kulikov A.N.1, Kazak A.A.1, Vasiliev A.S.1
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Affiliations:
- S.M. Kirov Military Medical Academy
- Issue: Vol 13, No 2 (2020)
- Pages: 9-14
- Section: Original researches
- URL: https://journals.eco-vector.com/ov/article/view/25905
- DOI: https://doi.org/10.17816/OV25905
- ID: 25905
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Abstract
Aim. To study the representativity of macular edema mapping using en face optical coherence tomography (OCT), retinal thickness map, and fluorescein angiography (FA).
Methods. In this retrospective cross-sectional study, 8 patients (15 eyes) with diabetic macular edema (2 females and 6 males, mean age 66.5 ± 8.1 years) were included. All patients OCT (retinal thickness map and en face OCT) and FA were performed. En face slab was constructed between inner plexiform layer and retinal pigment epithelium. The area of macular edema was measured by two masked graders independently.
Results. There was no statistically significant difference in the area of macular edema between FA, en face OCT, and retinal thickness maps, 12.7 ± 8.1, 14.5 ± 8.4, 10.4 ± 6.9 mm2, respectively (ANOVA × 3, p = 0.34). Intraclass correlation coefficient for three methods was 0.87 and 0.95, for individual and mean values, respectively.
Conclusion. En face OCT is an adequate non-invasive alternative for FA in evaluating the area of macular edema and planning of grid macular laser photocoagulation.
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About the authors
Dmitrii S. Maltsev
S.M. Kirov Military Medical Academy
Author for correspondence.
Email: glaz.med@yandex.ru
ORCID iD: 0000-0001-6598-3982
MD, PhD, Head of Medical Retina Division of Ophthalmology Department
Russian Federation, Saint PetersburgAlexey N. Kulikov
S.M. Kirov Military Medical Academy
Email: alexey.kulikov@mail.ru
MD, DSc, head of ophthalmology department
Russian Federation, Saint PetersburgAlina A. Kazak
S.M. Kirov Military Medical Academy
Email: ali-kazak@mail.ru
Medical student
Russian Federation, Saint PetersburgAlexander S. Vasiliev
S.M. Kirov Military Medical Academy
Email: shizolamp@gmail.com
MD, Ophthalmologist of the Ophthalmology Department
Russian Federation, Saint PetersburgReferences
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