Prognosing intraocular pressure compensation in primary open-angle glaucoma patients at medical and surgical treatment

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Abstract


Objective. Criteria specification and prognosis establishment of intraocular pressure compensation in primary open-angle glaucoma (POAG) patients at medical and surgical treatment based on integrated clinical and instrumental examination. Methods. 128 POAG subjects (234 eyes) receiving medical treatment were included in the study, surgery was performed in 42 patients (52 eyes). Results. The use of multiple clinical parameters into the statistical analysis leads to an increase in the probability of IOP compensation and correct prognosis (up to 84.0-98.4 % of cases) in medical treatment, and does not alter the prognosis accuracy at surgical treatment. In analysis of lower variables number, correct prognosis of IOP compensation at medical treatment can be established in 75.4-75.7 % of cases, and at surgical treatment - in 100 % of cases. The results of present study are the basis for a computer program development that could allow a practicing ophthalmologist to determine the prognosis of IOP compensation in a POAG-patient.

Ol'ga Vladimirovna Soljannikova

South Ural State Medical University

Email: solyannikova_ov@mail.ru
candidate of medical science, docent. Ophthalmology department

Ekaterina Viktorovna Berdnikova

South Ural State Medical University

Email: e.v.berdnikova@gmail.com
assiatant professor. Ophthalmology department

Valerij Fedorovich Ekgardt

South Ural State Medical University

Email: anita1@inbox.ru
doctor of medical science, professor. Continued professional education faculty, ophthalmology department

Victorya Nikolaevna Dmitrienko

Chelyabinsk Regional Clinical Hospital

ophthalmologist

  1. Алексеев В. Н., Малеванная О. А. Исследование качества жизни больных. Клиническая офтальмология. 2003; 3: 113-4.
  2. Алексеев В. Н., Левко М. А., Абуатийех А. М. Взаимосвязь центральной гемодинамики и характер течения начальной открытоугольной глаукомы. Глаукома. 2011; 1 (10): 8-11.
  3. Белова А. Н. Щепетова О. Н. Шкалы, тесты и опросники в медицинской реабилитации. М.: Антидор. 2002; 440.
  4. Ермолаев В. Г., Ермолаев А. В., Ермолаев С. В., Миронюк Н. Г. Качество жизни больных глаукомой. Современные наукоемкие технологии. 2008; 8: 18.
  5. Курышева, Н. И. Глаукомная оптическая нейропатия. М.: МЕДпресс-информ, 2006.
  6. Либман Е. С., Шахова Е. В. Слепота и инвалидность вследствие патологии органа зрения в России. Вестник офтальмологии. 2006; 1 (122): 35-7.
  7. Нестеров А. П. Первичная открытоугольная глаукома: патогенез и принципы лечения. Клин. офтальмология. 2000; 1 (1): 4-5.
  8. Приказ Минздрава России от 09.11.2012 N 862 н «Об утверждении стандарта специализированной медицинской помощи при глаукоме» (Зарегистрировано в Минюсте России 31.01.2013 № 26761).
  9. Маркелова Е. В., Кириенко А. В., Чикаловец И. В., Догадова Л. П. Характеристика системы цитокинов и ее роль в патогенезе первичных глауком. Фундаментальные исследования 2014; 2: 110-6.
  10. Glen F. C., Crabb D. P., Garway-Heath D. F. The direction of research into visual disability and quality of life in glaucoma [Electronic resource]. BMC Ophthalmology 2011; 19 (11). Mode of access: http://www.biomedcentral.com/1471-2415/11/19.
  11. Goldberg J. L. Glaucoma and the brain [Electronic resource]. Gleams. 2010; Sept. Mode of access: http://www.glaucoma.org/glaucoma/glaucoma-and-the-brain.php.
  12. Тezel G., Kaplan H. J., Zimmerman T. J., Ben-Hur T., Gibson G. E., Stevens B., Streit W. J., Wekerle H., Bhattacharya S. K., Borras T., Burgoyne C. F., Caspi R. R., Chauhan B. C., Clark A. F., Crowston J., Danias J., Dick A. D., Flammer J., Foster C. S., Grosskreutz C. L. The role of glia, mitochondria, and the immune system in glaucoma. Investigative Ophthalmology and Visual Science 2009; 3 (50): 1001-12.
  13. Quigley H. A. Number of people with glaucoma worldwide. Br. J. Ophthalmol. 1996; 5: 389-93.
  14. Quigley H. A., Cone F. E. Development of diagnostic and treatment strategies for glaucoma through understanding and modification of sclera and lamina cribrosa connective tissue. Cell and Tissue Research. 2013; 2 (353): 231-44.

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Copyright (c) 2015 Soljannikova O.V., Berdnikova E.V., Ekgardt V.F., Dmitrienko V.N.

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