Email this article 
On the problem of local antibiotic therapy in children with ocular surface diseases
- Authors: Fenkova O.G1, Fursova A.Z1, Gusarevich O.G2
-
Affiliations:
- Federal State Budgetary Institution of the Novosibirsk Region “State Novosibirsk regional clinical hospital”
- Federal State Budgetary Educational Institution “Novosibirsk State Medical University” of Ministry of the Healthcare of the Russian Federation
- Issue: Vol 9, No 1 (2016)
- Pages: 65-68
- Section: Articles
- URL: https://journals.eco-vector.com/ov/article/view/2945
- DOI: https://doi.org/10.17816/OV9165-68
- ID: 2945
Cite item
Open Access
Access granted
Abstract
The efficacy and safety of topical Azithromycin ophthalmic solution 1.5 % has been evaluated in treatment of bacterial conjunctivitis and post-traumatic keratitis in children, and the possibility of its use for prevention of infectious complications after ocular surface trauma. Topical Azithromycin ophthalmic solution 1.5 % was used in 32 children: with bacterial conjunctivitis (21), corneal foreign body (5), traumatic corneal erosion (3), post-traumatic keratitis (3). Topical Azithromycin ophthalmic solution 1.5% was shown to have a significant antibacterial activity and a convenient dosing schedule. No side effects, including eye irritation, have been noted. Conclusion: topical Azithromycin ophthalmic solution 1.5 % could be considered as the medication of choice in treatment of bacterial conjunctivitis and post-traumatic keratitis in children. It also could be used in the complex prevention of infections complications in eye surface traumatic lesions.
Keywords
Full Text
About the authors
Olga G Fenkova
Federal State Budgetary Institution of the Novosibirsk Region “State Novosibirsk regional clinical hospital”
Email: olga.fenkova@yandex
Anzhella Z Fursova
Federal State Budgetary Institution of the Novosibirsk Region “State Novosibirsk regional clinical hospital”
Email: anzhellafursova@ya.ru
Olga G Gusarevich
Federal State Budgetary Educational Institution “Novosibirsk State Medical University” of Ministry of the Healthcare of the Russian Federation
Email: olga.gusarevich@gmail.com
References
- Майчук Ю.Ф. Современная терапия конъюнктивитов у детей // Педиатрия. - 2007. - № 2. - С. 80-87. [Maichuk YF. Modern treatment of conjunctivitis in children. Pediatrics. 2007;(2):80-87. (in Russ).]
- Зубарева Л.Н., Гаврилюк А.С., Артамонова А.В. Первый опыт применения глазных капель Вигамокс у пациентов детского возраста // Вестник ОГУ. - 2011. - Т. 133. - № 14. - С. 151-153. [Zubareva LN, Gavrilyuk AS, Artamonov AV.The first experience with eye drops Vigamox in pediatric patients. Vestnik OGU. 2011: 133(14):151-153. (in Russ).]
- Воронцова Т.Н., Бржеский В.В., Михайлова М.В. Чувствительность и резистентность к антибактериальным препаратам микрофлоры конъюнктивальной полости у детей // Офтальмология. - 2012. - Т. 9. - № 1. - С. 3-7. [Vorontsova TN, Brzheskiy VV, Mikhailova MV. Sensitivity and resistance to antibiotics microflora conjunctival cavity in children. Ophthalmology. 2012;9(1):3-7. (in Russ).]
- Воронцова Т.Н., Бржеский В.В., Ефимова Е.Л. Микрофлора конъюнктивальной полости и её чувствительность к антибактериальным препаратам у детей в норме и при некоторых воспалительных заболеваниях глаз // Офтальмологические ведомости. - 2010. - № 2. - С. 61-65. [Vorontsova TN, Brzheskiy VV, Efimova EL. Conjunctival cavity microflora and its sensitivity to antibiotics in children in normal and some inflammatory diseases of the eye. Ophthalmology Journal. 2010; 2:61-65. (in Russ).]
- Майчук Ю.Ф. Современные возможности терапии конъюнктивитов. В кн.: Труды XVII Российского национального конгресса «Человек и лекарство». - М., 2011. - Т. 2. - С. 215-225. [Maichuk YF. Modern possibilities of treatment of conjunctivitis. In: Proceedings of the XVII Russian National Congress “Man and medicine”. Moscow; 2011;2:215-225. (in Riss).]
- Осокина Ю.Ю. Роль микрофлоры в развитии дакриоцистита новорожденных: Автореф. дис. … канд. мед. наук. - Красноярск, 2006. [Osokina YY. The role of the microflora in the development of neonatal dacryocystitis: [dissertition]. Krasnoyarsk; 2006. (in Russ).]
- Околов И.Н., Кафтырева Л.А. Резистентность коагулазонегативных стафилококков, выделенных от больных с конъюнктивитами, к антибактериальным препаратам // Новое в офтальмологии. - 2006. - Т. 4. - С. 34-36. [Okolov IN, Kaftyreva LA. Resistance of coagulase-negative staphylococci isolated from patients with conjunctivitis to antibiotics. New in ophthalmology. 2006;4:34-36. (in Russ).]
- Митрохин С.Д. Азитромицин: обоснованность применения в терапии различной инфекционной патологии // Трудный пациент. - 2009. - Т. 7. - № 4-5. - С. 53-58. [Mitrokhin SD. Azithromycin: the validity of the application in the treatment of various infectious diseases. The difficult patient. 2009;7(4-5):53-58. (in Russ).]
Supplementary files
