急性角膜水肿:诊断和治疗

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详细

急性角膜水肿是一种以后弹力膜破裂导致的角膜基质水肿为特征的疾病。

研究目的:分析急性角膜水肿患者的诊断和治疗结果。

材料和方法:该研究组中包括42例(47只眼)急性角膜水肿患者。5例患者两只眼同时或先后发生急性角膜水肿。平均年龄为28.7 ± 10.1岁(19岁到54岁),男31例,女11例,观察期为5年。在没有药物治疗作用或术后
并发症的情况下:向眼前房注入10%气体(C3F8, SF6),羊膜移植,板层角膜移植,深层前角膜移植,穿透性角
膜移植。

结果:急性角膜水肿发作前的平均病程为12.6 ± 4.6年。11.9%的患者先前未诊断出角膜扩张。局部水肿的角膜厚度为692 ± 98 μm,全水肿的角膜厚度为1200 ± 220 μm。与局部和部分水肿相比,次全和全角膜水肿其损伤程度、后弹力层脱离的高度以及破裂边缘分叉更明显(χ2, p < 0.001)。将10%的气体-空气混合物(C3F8, SF6)注入部分和次全角膜水肿患者的眼前房,可以明显加快水肿缓解。

结论:这类病例的分析结果表明,根据急性角膜水肿的严重程度采用不同的治疗方案。

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作者简介

Galina Sitnik

State Educational Establishment “Belarusian medical academy of postgraduate education”

编辑信件的主要联系方式.
Email: sitnik_halina@mail.ru
ORCID iD: 0000-0003-4675-9963

PhD, Associate Professor of Ophthalmology Chair

白俄罗斯, Minsk

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