The influence of some general diseases for changes on the ocular surface after trabeculectomy
- 作者: Аntonova А.V.1,2, Nikolaenko V.P.1,2, Brzheskiy V.V.3, Vuks A.J.4, Koskin S.A.5,6
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隶属关系:
- Saint Petersburg Multifield Hospital No. 2
- Saint Petersburg State University
- Saint Petersburg State Pediatric Medical University
- V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
- Kirov Military Medical Academy
- Pavlov Institute of Physiology of the Russian Academy of Sciences
- 期: 卷 17, 编号 1 (2024)
- 页面: 7-20
- 栏目: Original researches
- ##submission.dateSubmitted##: 02.09.2023
- ##submission.dateAccepted##: 18.01.2024
- ##submission.datePublished##: 09.03.2024
- URL: https://journals.eco-vector.com/ov/article/view/568993
- DOI: https://doi.org/10.17816/OV568993
- ID: 568993
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BACKGROUND: By now, possible effects of diabetes mellitus and arterial hypertension on the ocular surface changes after trabeculectomy have not been evaluated.
AIM: Analysis of the effects of arterial hypertension therapy and diabetes mellitus on the ocular surface changes after trabeculectomy.
MATERIALS AND METHODS: The study group consisted of 443 patients, including those with arterial hypertension (179 patients), non insulin dependent compensated type 2 diabetes mellitus (25 patients) and their combination (53 persons), operated in 2016–2020 in the City Multifield Hospital No. 2, Saint-Petersburg, for primary open-angle noncompensated glaucoma and then observed for 6 to 24 months. The dynamics of ocular surface disease index (OSDI), tear film break-up time (TBUT), and amount of total tear production has been studied.
RESULTS: The probability of the trabeculectomy success did not depend on the concomitant comorbidity. In contrast to intraocular pressure, the criteria for subjective and objective assessment of the ocular surface state were not subject to such obvious changes. In diabetic patients, the studied criteria have not changed compared to the baseline.
CONCLUSIONS: The mentioned systemic diseases do not influence the state of the ocular surface in patients with glaucoma, and are not an independent risk factor for the failure of the IOP-lowering surgical procedure. The presence of diabetes mellitus prevents the accompanying a successful trabeculectomy regression of symptoms and clinical and functional signs of dry eye disease.
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作者简介
Аnastasiia Аntonova
Saint Petersburg Multifield Hospital No. 2; Saint Petersburg State University
编辑信件的主要联系方式.
Email: dr.antonova.av@gmail.com
ORCID iD: 0000-0002-2639-2765
SPIN 代码: 2166-3936
Ophthalmologist
俄罗斯联邦, 5 Uchebnyi lane, Saint Petersburg, 194354; 7–9 Universitetskaya embankment, Saint Petersburg, 199034Vadim Nikolaenko
Saint Petersburg Multifield Hospital No. 2; Saint Petersburg State University
Email: dr.Nikolaenko@mail.ru
ORCID iD: 0000-0002-6393-1289
SPIN 代码: 4906-2542
MD, PhD, Doc. Sci. (Med.), Head of Ophthalmology Department, professor Otorhinolaryngology and ophthalmologydepartment
俄罗斯联邦, 5 Uchebnyi lane, Saint Petersburg, 194354; 7–9 Universitetskaya embankment, Saint Petersburg, 199034Vladimir Brzheskiy
Saint Petersburg State Pediatric Medical University
Email: vvbrzh@yandex.ru
ORCID iD: 0000-0001-7361-0270
SPIN 代码: 5442-0989
MD, Dr. Sci. (Med.), Professor
俄罗斯联邦, Saint PetersburgAlexandr Vuks
V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology
Email: ayavuks@bekhterev.ru
ORCID iD: 0000-0002-6700-0609
SPIN 代码: 2290-4021
俄罗斯联邦, Saint Petersburg
Sergey Koskin
Kirov Military Medical Academy; Pavlov Institute of Physiology of the Russian Academy of Sciences
Email: eyemillenium@mail.ru
ORCID iD: 0000-0003-3994-9232
SPIN 代码: 9882-6880
Dr. Sci. (Medicine), Professor
俄罗斯联邦, Saint Petersburg; Saint Petersburg参考
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