Neurophysiological Factors Associated with Compression and Reflex Mechanisms of Lower Back Pain
- Authors: Barinova I.A.1, Erkhova L.N.1, Zhadnov V.A.2, Zorin R.A.2, Kiryukhina N.N.1, Kosolapov A.A.1, Leonov G.A.2, Burshinov A.O.2
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Affiliations:
- Ryazan Regional Clinical Hospital
- Ryazan State Medical University
- Issue: Vol 31, No 4 (2023)
- Pages: 593-600
- Section: Original study
- URL: https://journals.eco-vector.com/pavlovj/article/view/303663
- DOI: https://doi.org/10.17816/PAVLOVJ303663
- ID: 303663
Cite item
Abstract
Introduction: Vertebrogenic pain syndromes (PSs) in the lower back (LB) are among the most common neurological disorders in the population. Currently, clinical, neurophysiological and neuroimaging characteristics are used as predictors of the course and effectiveness of the treatment for vertebrogenic PSs in the LB.
Aim: To identify the neurophysiological factors associated with compression and reflex mechanisms of PSs in the LB for their differentiation in complicated diagnostic cases.
Materials and methods: The study included 73 patients, 43 of them men and 30 women of the mean age 46.5 years. Based on the results of clinical neurological examination and the magnetic resonance imaging data, reflex vertebrogenic PSs (lumboischialgia) were verified in 40 cases, and radiculopathy of L5 and/or S1 (compression vertebrogenic PSs) in 33 cases. The patients underwent stimulation electroneuromyography with record of motor and sensory responses from the lower limbs, of F- and H-response, and examination of heart rate variability.
Results: Logit regression analysis was used to create models permitting to divide patients into groups with different mechanisms of PSs based on the neurophysiological parameters. The first model demonstrated high sensitivity in the identification of predominantly compression vertebrogenic disorders with the independent factors being the mean F-wave latency and the sensory response amplitude. The second model was more sensitive in identification of reflex PSs with the main predictors being the F-response amplitude and heart rate variability parameters.
Conclusion: The identified factors reflect the role of conduction disorders in compression PSs, as well as the involvement of segmental motor neuronal apparatus and autonomic regulatory mechanisms in the reaction in reflex PSs, which are additional sources of information in taking medical decisions in complicated diagnostic cases.
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About the authors
Irina A. Barinova
Ryazan Regional Clinical Hospital
Author for correspondence.
Email: barinova-irina-a2@yandex.ru
ORCID iD: 0000-0001-5384-5208
SPIN-code: 4545-1196
Postgraduate Student of the Department of Neurology and Neurosurgery
Russian Federation, RyazanLiliya N. Erkhova
Ryazan Regional Clinical Hospital
Email: shu-lilya1@yandex.ru
ORCID iD: 0009-0005-9097-6799
SPIN-code: 3737-7064
MD, Cand. Sci. (Med.)
Russian Federation, RyazanVladimir A. Zhadnov
Ryazan State Medical University
Email: vladimir.zhadnov@mail.ru
ORCID iD: 0000-0002-5973-1196
SPIN-code: 1632-5083
MD, Dr. Sci. (Med.), Professor
Russian Federation, RyazanRoman A. Zorin
Ryazan State Medical University
Email: zorin.ra30091980@mail.ru
ORCID iD: 0000-0003-4310-8786
SPIN-code: 5210-5747
MD, Dr. Sci. (Med.), Associate Professor
Russian Federation, RyazanNadezhda N. Kiryukhina
Ryazan Regional Clinical Hospital
Email: centerrsc@mail.ru
ORCID iD: 0000-0003-2561-5960
SPIN-code: 2441-3020
MD, Cand. Sci. (Med.);
Russian Federation, RyazanAndrey A. Kosolapov
Ryazan Regional Clinical Hospital
Email: kocolapov2@rambler.ru
ORCID iD: 0000-0001-7593-2353
SPIN-code: 3413-4917
MD, Cand. Sci. (Med.)
Russian Federation, RyazanGennadiy A. Leonov
Ryazan State Medical University
Email: lionlion56.leonov@yandex.com
ORCID iD: 0000-0001-5780-1675
SPIN-code: 5115-3996
MD, Dr. Sci. (Med.), Associate Professor
Russian Federation, RyazanAleksandr O. Burshinov
Ryazan State Medical University
Email: baomz@mail.ru
ORCID iD: 0009-0001-1708-2642
SPIN-code: 8792-9686
MD, Dr. Sci. (Med.), Associate Professor
Russian Federation, RyazanReferences
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