MORPHOLOGICAL CHARACTERISTICS OF HUMAN TRACHEA AND BNOCHI GLANDS OF SMOKING AND NON-SMOKING ADULT MEN

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Abstract


This work describes macroscopic, hystological and morphometrical study of human trachea and bronchi glands of smoking and non-smoking adult men. The study shows that number of excretory ducts of the glands in trachea, main right and distal bronchus is 3-4 times larger for smokers, rather that for non-smokers. Also, a growth of volumetric fraction of bronchial glands and mucous acini in main right and common bronchi was reliably identified for smokers versus non-smokers. These findings indicate that smoking not only increases the volumetric fraction of glads in bronchial wall, but also leads to growth of number of glands.

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МОРФОЛОГИЧЕСКАЯ ХАРАКТЕРИСТИКА ЖЕЛЕЗ ТРАХЕИ И БРОНХОВ У КУРЯЩИХ И НЕКУРЯЩИХ МУЖЧИН ЗРЕЛОГО ВОЗРАСТА

About the authors

E V Kolesnicova

E I Sidorova

Email: at976@yandex.ru

L P Mihailova

O V Makarova

References

  1. Автандилов Г.Г. Введение в количественную патологическую морфологию / Г.Г. Автандилов. – М.: Медицина, 1980. – 216 с.
  2. Антонов Н.С. Хроническая обструктивная болезнь легких / Н.С. Антонов; под ред. А.Г. Чучалина. – М.: Изд-й дом «Атмосфера», 2008. – 367 с.
  3. Бармина Г.В. Морфология первичного хронического бронхита: гистохимическое, электронно-микроскопическое и морфометрическое исследование слизистой оболочки бронхов: дис. канд. мед. наук / Г.В. Бармина. – М., 1991. – 164 с.
  4. Непомнящих Г.И. Биопсия бронхов: морфогенез общепатологических процессов в легких / Г.И. Непомнящих. – М.: Изд-во РАМН, 2005. – 384 с.
  5. Сапин М.Р. Малые железы пищеварительной и дыхательной системы./ Д.Б. Никитюк, В.Б. Шадлинский, Н.Т. Мовсумов. – М.; Элиста: АПП Джангар, 2001. – 136 с.
  6. Haustein K.-O. Tobacco or health / K. Haustein. – N.Y.: Springer, 2003.
  7. Muller B. Impaired action of thyroid hormone associated with smoking in women with hypothyroidism / H. Zulewski [et al.] // N. Engl. J. Med. – 1995. – Vol. 333. – P. 964-969.
  8. Liu X. Airway glandular development and stem cells / Driskell R.R, Engelhardt J.F. // Curr. Top. Dev. Biol. – 2004. – №64. – P. 33-56.
  9. Liu X1. The Glandular Stem/Progenitor Cell Niche in Airway Development and Repair / John F. Engelhardt // Proc. Am. Thorac. Soc. – 2008. – Vol. 5. – P. 682-688.
  10. Zhu Y. Cultured human airway epithelial cells (Calu-3): a model of human respiratory function, structure, and inflammatory responses/ A. Chidekel, T. H. Shaffer // Critical сare research and practice. – 2010. –Vol. 2010. – P. 8.
  11. Zhu J. Plasma cells and IL-4 in chronic bronchitis and chronic obstructive pulmonary disease / Y. Qiu [et al.] // Am. J. Respir. Crit. Care. Med. – 2007. – Vol. 175, № 11. – P. 1125-1133.

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Copyright (c) 2012 Kolesnicova E.V., Sidorova E.I., Mihailova L.P., Makarova O.V.

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