L-NORVALIN AND ISCHEMICAL PRECONDITIONING ACTION MECHANISMS ANALYSIS AT LIVER ISCHEMIA/REPERFUSION

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Abstract


In this article ischemical preconditioning and L-norvalin efficacy and mechanisms of action pharmacological analysis at liver experimental ischemia/reperfusion were made. During investigation ischemical preconditioning high effectiveness totally wasn’t blocked by glibenclamide showed. L-norvaline also showed marked hepatoprotective effect abolished by glibenclamide just partly.

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АНАЛИЗ МЕХАНИЗМОВ РЕАЛИЗАЦИИ ГЕПАТОПРОТЕКТОРНОГО ДЕЙСТВИЯ L-НОРВАЛИНА И ИШЕМИЧЕСКОГО ПРЕКОНДИЦИОНИРОВАНИЯ ПРИ ИШЕМИИ/РЕПЕРФУЗИИ ПЕЧЕНИ

About the authors

M V Pokrovsky

Email: mpokrovsky@yandex.ru

D V Lopatin

S A Alehin

D I Kolmykov

L V Ivanova

V D Lucenko

S L Speransky

I V Suhoterin

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Copyright (c) 2013 Pokrovsky M.V., Lopatin D.V., Alehin S.A., Kolmykov D.I., Ivanova L.V., Lucenko V.D., Speransky S.L., Suhoterin I.V.

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