ST段心肌梗死患者各种原因的死亡率因再灌注治疗类型而异(RYAZAN地区数据,2018-2020)
- 作者: Parshikova E.N.1, Filippov E.V.2
-
隶属关系:
- Lubertsy Regional Hospital
- Ryazan State Medical University
- 期: 卷 28, 编号 4 (2020)
- 页面: 479-487
- 栏目: Original study
- ##submission.dateSubmitted##: 28.10.2020
- ##submission.dateAccepted##: 12.11.2020
- ##submission.datePublished##: 15.12.2020
- URL: https://journals.eco-vector.com/pavlovj/article/view/48650
- DOI: https://doi.org/10.23888/PAVLOVJ2020284479-487
- ID: 48650
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详细
目的:评估ST段抬高型心肌梗死(STEMI)患者的死亡率和全因死亡率,这取决于再灌注治疗的类型。
材料与方法1456例ST段抬高型急性冠脉综合征住院患者中,随机抽取848例进行分析。关于终点(任何原因造成的死亡)的信息收集持续了18个月。目前的数据截至2020年10月1日,随访的中位数为20.8 [17.4; 23.6]个月。
结果。未接受再灌注治疗的患者中,18个月死亡率最高(42.3%)。同时溶栓治疗(TLT)组和未进行再灌注的组在30天内的死亡率没有显着差异(20.3%vs 26.2%,p> 0.05)。经皮冠状动脉介入治疗(PCI)组的住院30天,12个月,18个月全因死亡率分别为8.4%,10.6%,16.6%和18.3%,与对照组相比明显降低。未接受再灌注的患者(分别为19.5%,26.2%,36.2%和42.3%,p <0.05)。达到18个月里程碑时,终点频率的差异最显著:在未再灌注的个体组中,致死率为42.3%,高于TLT组(27.1%)、PCI组(18.3%)和TLT+PCI组(13.1%)。
结果。8个月的随访中,药物介入治疗组和直接PCI组的各种原因的死亡率最低,未接受再灌注治疗组的死亡率最高。
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作者简介
Elena Parshikova
Lubertsy Regional Hospital
Email: philpoiuy@yandex.ru
ORCID iD: 0000-0003-0349-3456
SPIN 代码: 2809-2781
Head of the Emergency Department
俄罗斯联邦, Lubertsy, Moscow regionEvgenii Filippov
Ryazan State Medical University
编辑信件的主要联系方式.
Email: dr.philippov@gmail.com
ORCID iD: 0000-0002-7688-7176
SPIN 代码: 2809-2781
Researcher ID: O-1490-2016
MD, PhD, Head of the Department of Outpatient Therapy and Preventive Medicine
俄罗斯联邦, Ryazan参考
- Alkhalil M, Choudhury RP. Reperfusion Treatment in Late Presentation Acute Myocardial Infarction: Timing Is Not Everything. Circulation: Cardiovascular Interventions. 2018;11(9):e007287. doi:10. 1161/CIRCINTERVENTIONS.118.007287
- Erlikh AD. Six-month outcomes in acute coronary syndrome patients included in the registry Record-3. Russian Journal of Cardiology. 2017;22(11):8-14. (In Russ). doi: 10.15829/1560-4071-2017-11-8-14
- Martsevich SYu, Semenova YuV, Kutishenko NP, et al. LIS-3 register of the acute coronary syndrome: what has changed in a «portrait» of a patient and short-term outcomes of the disease compared to LIS-1 register. Rational Pharmacotherapy in Cardiology. 2017;13(1):63-8. (In Russ). doi:10. 20996/1819-6446-2017-13-1-63-68
- Kutishenko NP, Kalaydzhyan EP, Sichinava DP, et al. Outpatient registry of patients with acute myocardial infarction (PROFILE-IM): data on prehospital therapy in comparison with the LIS-3 registry. Rational Pharmacotherapy in Cardiology. 2018;14(1):88-93. (In Russ). doi: 10.20996/1819-6446-2018-14-1-88-93
- Erlikh AD. Twelve months outcomes in patients with acute coronary syndrome, by the national registry RECORD-3. Russian Journal of Cardiology. 2018;(3):23-30. (In Russ). doi: 10.15829/1560-4071-2018-3-23-30
- Russian Statistical Yearbook 2019. Moscow; 2019. Available at: https://rosstat.gov.ru/storage/media-bank/Ejegodnik_2019.pdf. Accessed: 2020 October 27. (In Russ).
- Sanchis-Gomar F, Perez-Quilis C, Leischik R, et al. Epidemiology of coronary heart disease and acute coronary syndrome. Annals of Translational Medicine. 2016;4(13):256. doi: 10.21037/atm.2016.06.33
- Biery DW, Berman AN, Singh A, et al. Association of Smoking Cessation and Survival Among Young Adults with Myocardial Infarction in the Partners YOUNG-MI Registry. JAMA Network Open. 2020; 3(7):e209649. doi: 10.1001/jamanetworkopen.2020. 9649
- Fazel R., Joseph T.I., Sankardas M.A., et al. Comparison of Reperfusion Strategies for ST-Segment-Elevation Myocardial Infarction: A Multivariate Network Meta-analysis. Journal of the American Heart Association. 2020;9(12):e015186. doi:10. 1161/JAHA.119.015186
- Ibanez B, James S, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). European Heart Journal. 2018;39(2):119-77. doi: 10.1093/eurheartj/ehx393
- Order of the Government of the Ryazan region of 27 June 2019 №301-p «Ob utverzhdenii regional’noy programmy Ryazanskoy oblasti «Bor’ba s serdechno-sosudistymi zabolevaniyami». Available at: http://docs.cntd.ru/document/553385694. Accessed: 2020 October 27. (In Russ).
- Peiyuan H, Jingang Y, Haiyan X, et al. The Comparison of the Outcomes between Primary PCI, Fibrinolysis, and No Reperfusion in Patients ≥ 75 Years Old with ST-Segment Elevation Myocardial Infarction: Results from the Chinese Acute Myocardial Infarction (CAMI) Registry. PLoS One. 2016; 11(11):e0165672. doi: 10.1371/journal.pone.0165672
- Limwattananon C, Jaratpatthararoj J, Thungthong J, et al. Access to reperfusion therapy and mortality outcomes in patients with ST-segment elevation myocardial infarction under universal health coverage in Thailand. BMC Cardiovascular Disorders. 2020;20. doi: 10.1186/s12872-020-01379-3
- Lozhkina NG, Khasanova MK, Stafeeva EA, et al. Prediction of remote outcomes of acute myocardial infarction with stable ST-segment elevation on ECG in real clinical practice. Modern Problems of Science and Education. 2018;(6). Available at: http://science-education.ru/ru/article/view?id=28172. Accessed: 2020 October 27. (In Russ).