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The paper presents the results of a comprehensive examination and treatment of 158 children and adolescents with nonossifying bone fibroma and skeleton, who referred for specialized medical aid in clinic of Scientific and Research Institute for Children's Orthopedics n. a. G. I. Turner from 1980 to 2013. We defined diagnostic value and the criteria for identifying lesions using X-ray, computed tomography and radionuclide methods. We emphasized the dynamic variability of clinical and radiological manifestations of the pathological process in nonossifying bone fibroma and skeleton and related difficulties in the diagnosis. Accurate indications for the conservative and surgical treatment were pointed out.

About the authors

Nikolai Georgievich Chigvariya

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, PhD, senior research associate of the department of maxillofacial surgery

Aleksander Pavlovich Pozdeev

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, PhD, DMedSc, Professor, chief research associate of the department of bone pathology

Artur Nuralievich Bergaliev

FSBI “Scientific and Research Institute for Children’s Orthopedics n. a. G. I. Turner” under the Ministry of Health of the Russian Federation

MD, PhD, DMedSc, head of the research laboratarial department


  1. Батраков С. Ю. Метафизарный фиброзный дефект кости у детей (клиника, диагностика, лечение): Автореф. дис.. канд. мед. наук. М., 2002. 21 с.
  2. Бекзадян Г. Р., Талантов В. А. Фиброзные кортикальные дефекты в метафизах костей // Вопросы онкологии. 1968. Т. 14, № 5. С. 39-45.
  3. Волков М. В. Неоссифицирующаяся фиброма кости у детей // Хирургия. 1989. № 11. С. 82-86.
  4. Волков М. В., Алексеенко А. А. Микрофокусная рейс-графия костей в патологии опорно-двигательной системы у детей // Ортопедия, травматология и протезирование. 1990. № 6. С. 12-15.
  5. Arata M. A., Peterson H. A., Dahlin D. C. Pathological fractures through non-ossifying fibromas // J. Bone Joint Surg. 1981. Vol. 63-A, № 6. P. 980-988.
  6. Caffey J. On fibrous defects in cortical walls of growing tubular bones: their radiologic appearance, structure, prevalence, natural course, and diagnostic significance // Advances in Pediatrics. 1955. Vol. VII. P. 13-51.
  7. Campanacci M. Bone and soft tissue tumors. New York: Springer, 1990. 1131 p.
  8. Cunningham J. B., Ackerman L. V. Metaphyseal fibrous defects // J. Bone Joint Surg. 1956. Vol. 38-A, № 4. P. 797-808.
  9. Fechner R. E., Mills S. E. Atlas of tumor pathology: tumors of the bones and joints. Washington, D. C.: Armed Forces Institute of Pathology, 1993. 300 p.
  10. Fletcher C. D., Unni K. K., Mertens F. World Health Organization classification of tumours. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press, 2002. 429 p.
  11. Freyschmidt J., Saure D., Dammenhain S. Der fibröse metaphysäre defekt (fibröser kortikalisdefekt, nicht ossifizierendes knochenfibrom). Mitteilung I: Untersuchungen zur häufigkeit // Fortschr. Röntgenstr. 1981. Bd. 134, H. 2. S. 169-177.
  12. Garlipp M. Zur diagnostik und therapie des nichtossifizierenden knochenfibroms // Kinderärztliche praxis. 1978. Bd. 46, H. 9. S. 449-454.
  13. Jaffe H. L. Tumors and tumorous conditions of the bones and joints. Philadelphia: Lea and Febiger, 1958. 629 p.
  14. Klümper A. Differentialdiagnose aneurysmatische knochenzyste und nicht ossifizierendes fibrom // Fortschr. Röntgenstr. 1977. Bd. 127, H. 3. S. 261-264.
  15. Phelan J. T. Fibrous cortical defect and nonosseous fibroma of bone // Surgery, Gynecology & Obstetrics. 1964. Vol. 119, № 4. P. 807-810.
  16. Ritschl P., Karnel F. Zur Pathogenese des fibrösen kortikalisdefektes und nicht ossifizierenden knochenfibromes // Z. Orthop. 1986. Bd. 124, H. 6. S. 682-687.
  17. Schajowicz F., Sissons H. A., Sobin L. H. The World Health Organization's Histologic Classification of bone tumors. A commentary on the second edition // Cancer. 1995. Vol. 75, № 5. P. 1208-1214.
  18. Selby S. Metaphyseal cortical defects in the tubular bones of growing children // J. Bone Joint Surg. 1961. Vol. 43-A, № 3. P. 395-400.
  19. Sontag L. W., Pyle S. I. The appearance and nature of cyst-like areas in the distal femoral metaphyses of children // Am. J. Roentgenol. 1941. Vol. 46, № 2. P. 185-188.



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Copyright (c) 2014 Chigvariya N.G., Pozdeev A.P., Bergaliev A.N.

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