使用创新技术治疗热伤患者的可能性（临床病例描述）

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论证。严重烧伤的受害者需要专业和高科技援助。这类病人的治疗结果通常取决于移植的时间和在供体资源短缺的情况下切除坏死组织和恢复皮肤的外科治疗的数量。在这方面，开发和引入创新技术，利用合成涂层暂时封闭烧伤创面，以及在创面创造最佳条件，以植入具有高穿孔指数的皮肤移植物，都是相关的。

临床观察。本文介绍了一个应用创新创面涂层和细胞技术，通过早期手术治疗，成功治疗儿童严重烧伤部位火焰伤（货车伤）的临床案例。

讨论。我们认为转移到多学科医院的专科是成功治疗大面积烧伤患者的基本时刻。在烧伤中心的情况下，手术治疗的目的是在伤口出现炎症反应之前，将深部病变最大面积的坏死组织切除。随后，积极的手术策略为伤口准备延迟的塑料闭合，伤口覆盖物的使用和将细胞技术引入临床实践，确保了患者的成功治疗，因为自体皮肤移植的早期适应和最大限度地减少其退化的风险，加速细胞的上皮形成。

结论。早期将严重烧伤的儿童转移到专门的烧伤中心，积极的手术策略，创新的伤口涂层和细胞技术的使用，在治疗深度烧伤的关键区域的患者，可以挽救生命，成功恢复受损的皮肤，为早期康复措施的实施创造最佳条件。

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作者简介

Sergey B. Bogdanov

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University

编辑信件的主要联系方式.
Email: bogdanovsb@mail.ru
ORCID iD: 0000-0001-9573-4776
SPIN 代码: 2465-5462
Scopus 作者 ID: 57202018252

MD, PhD, Dr. Sci. (Med.)

俄罗斯联邦, Krasnodar; Krasnodar

Anton V. Karakulev

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University

Email: karakulev797@gmail.com
ORCID iD: 0000-0002-5477-5755
SPIN 代码: 9687-7717

MD, PhD student

俄罗斯联邦, Krasnodar; Krasnodar

Andrey V. Polyakov

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University

Email: 350000@mail.ru
ORCID iD: 0000-0003-1065-1352
SPIN 代码: 5317-8105

MD, PhD, Cand. Sci. (Med.), Associate Professor

俄罗斯联邦, Krasnodar; Krasnodar

Irina V. Gilevich

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1; Kuban State Medical University

Email: giliv@mail.ru
ORCID iD: 0000-0002-9766-1811
SPIN 代码: 3911-1488
Scopus 作者 ID: 55614951400

MD, PhD, Cand. Sci. (Med.)

俄罗斯联邦, Krasnodar; Krasnodar

Anatoly A. Petrov

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1

Email: napetrovaa@gmail.com
ORCID iD: 0000-0002-1234-3399

MD, Surgeon

俄罗斯联邦, Krasnodar

Yuriy V. Ivaschenko

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1

Email: yvi85@bk.ru
ORCID iD: 0000-0001-8242-2626

MD, Orthopedic and trauma surgeon

俄罗斯联邦, Krasnodar

Alesya M. Karakuleva

City Polyclinic Number 12 of the City of Krasnodar

Email: nazarenkova93@mail.ru
ORCID iD: 0000-0002-2258-206X

MD, Pediatrician

俄罗斯联邦, Krasnodar

Natalia A. Filipchenko

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1

Email: ozhogovycentr@mail.ru
ORCID iD: 0000-0002-0272-4606

MD, Pediatrician

俄罗斯联邦, Krasnodar

Elena A. Titarenko

Scientific Research Institution — S.V. Ochapovsky Regional Clinical Hospital No. 1

Email: evenasoroka77@gmail.com
ORCID iD: 0000-0003-1425-1698

MD, Pediatrician

俄罗斯联邦, Krasnodar

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2. 图 1 P.患者，9岁：a——受伤后3个月，采用原发性和延迟性自体成形术进行坏死切除的结果；b——背部形成肉芽伤口（受伤后3.5个月）

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3. 图 2 进行延迟自体皮肤成形术的过程：a——用氯化钠等渗溶液中的悬浮液进行冲洗，自体成形术后细胞中的自体成纤维细胞的穿孔率为1:6；b——使用《ChitoPran》伤口敷料

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4. 图 3 治疗结果：a——出院前恢复的皮肤；b——受伤后7个月的视图

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版权所有 © Bogdanov S., Karakulev A., Polyakov A., Gilevich I., Petrov A., Ivaschenko Y., Karakuleva A., Filipchenko N., Titarenko E., 2022

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