Androgenic condition and statins: contradictions in modern literature

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Abstract

Pathological age-related involution of the male reproductive system is characterized by combined clinical manifestations, which are designated by the terms age-related androgen deficiency syndrome, andropause, and male menopause. In modern foreign literature, the term “late hypogonadism” is more often used; in domestic literature, “age-related androgen deficiency” is utilized. The problem of late hypogonadism has gone beyond the scope of endocrinology and sexopathology. Currently, it has acquired an interdisciplinary character and gained attention from gerontologists, cardiologists, diabetologists, andrologists, and other specialists. The medical and social significance of age-related androgen deficiency syndrome is determined by the fact that it worsens the quality of life and is a risk factor for death, primarily from cardiovascular diseases. The review article presents modern ideas regarding the effect of statins on the androgen status of men with cardiac pathology and hypercholesterolemia.

About the authors

Arsen V. Osipov

Stavropol Regional Clinical Consulting and Diagnostic Center

Author for correspondence.
Email: 475888@ro.ru
ORCID iD: 0009-0003-1226-373X

MD

Russian Federation, Stavropol

Tatiana I. Derevyanko

Stavropol State Medical University

Email: uro-dep@yandex.ru
ORCID iD: 0000-0003-1659-319X
SPIN-code: 4095-3653

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Stavropol

Nadezhda V. Agranovich

Stavropol State Medical University

Email: nagranovich@mail.ru
ORCID iD: 0000-0002-3717-7091
SPIN-code: 8751-8613

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Stavropol

Roman S. Frantsev

Stavropol State Medical University; City Clinical Hospital of Emergency Medical Care

Email: francuz26@mail.ru
ORCID iD: 0009-0000-8893-7938
SPIN-code: 9050-5976

MD, Cand. Sci. (Medicine)

Russian Federation, Stavropol; Stavropol

Gayane G. Babasheva

Stavropol State Medical University

Email: babasheva.gayana@yandex.ru
ORCID iD: 0009-0005-8825-0163
SPIN-code: 6831-5890

MD, Cand. Sci. (Medicine)

Russian Federation, Stavropol

Olga A. Aleksandrova

Stavropol State Medical University

Email: aleksandrovaolga26@mail.ru
ORCID iD: 0009-0003-2639-2401
SPIN-code: 5745-3207

MD

Russian Federation, Stavropol

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