Urology reports (St. - Petersburg)

Quarterly medical peer-review journal for practitioners and researchers is published since 2011.

  • Since 2018 selected papers are translated and published in English
  • Since 2020 - in Chinese.
  • Special Issues (conference proceedings) are published in Russian.

Editor-in-Cheif

Publisher

  • Eco-Vector Publishing house (link)

About

The journal «Urology reports (St. - Petersburg)» publish articles with original studies results, scientific reviews, lectures for practitioners, clinical observations and case reports, as well as information about important dates in the history of urology and the results of congresses and conferences. The journal accepts results of experimental and clinical studies regarding epidemiology, etiology, pathogenesis, clinical course, diagnosis, treatment and prevention of urological diseases. The articles touch upon the problems of general urology, neurourology, andrology, oncourology, urogynecology, reproductive health of men and other fields, as well as related specialties.

The journal is published with the assistance of the Department of Urology Academician I.P. Pavlov First St. Petersburg State Medical University and St. Petersburg Society of Urology named after S.P. Fedorov.

The journal is intended for urologists, researchers and faculty of medical schools, as well as specialists in related specialties.

Indexing

  • SCOPUS
  • Russian Science Citation Index
  • Google Scholar
  • Ulrich's Periodicals directory
  • CyberLeninka
  • Dimensions
  • CNKI
  • Crossref

Publications

  • No obligatory APC or ASC
  • Hybrid access (optional Open Access with distribution with the CC BY-NC-ND 4.0 License)
  • Quarterly publications of regular issues
  • Online First continuously publication 
  • English and Russian abstracts and full-texts 

Announcements More Announcements...

 

Editorial news: 'Urology Reports (St. Petersburg)' journal accepted for indexing in SCOPUS

Posted: 20.07.2023

 

The 'Urology Reports (St. Petersburg)' journal has been successfully evaluated and accepted for indexing in the SCOPUS database.

The Scopus Content Selection & Advisory Board (CSAB) has reviewed the journal and approved it for coverage. The message from CSAB was received on 06.07.2023.

All articles published in the journal from 2023 are subject for indexation.


 

Current Issue

Open Access Open Access  Restricted Access Access granted  Restricted Access Subscription or Fee Access

Vol 13, No 4 (2023)

Cover Page

Full Issue

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Original articles

Pathomorphological restructuring of the buccal mucosa grafts during ureteroplasty (experimental and clinical study)
Guliev B.G., Avazkhanov Z.P., Droblenkov A.V., Vinnichuk S.A., Abdurakhmanov O.S.
Abstract

BACKGROUND: Currently for the plastic surgery of extended strictures of the pyeloureteral segment and proximal ureter a grafts from the buccal mucosa is used. Histological changes in these grafts in the postoperative period have not been sufficiently studied.

AIM: is to study the histological changes in the graft from the buccal mucosa used for ureteroplasty in an experiment and in patients at different times after surgery.

MATERIALS AND METHODS: The experimental part of the study was carried out on 10 animals (rabbits). We studied histological changes in the wall of the buccal mucosa graft used for ureteroplasty. Under general anesthesia a median laparotomy was performed, the ureter was mobilized along the middle third, a defect of about 1 cm was created. Next a buccal graft of 1.5 × 1 cm was cut out, which was sutured to the ureteral defect using the onlay technique. After 6 months nephroureterectomy was performed. Three parts of the ureter were identified: the replacement zone, 3 cm sections above and below it, followed by histological examination. The clinical part of the study consisted of a histological examination of biopsy samples obtained from 5 patients during ureteroscopy by pinching graft biopsy 12 months and 24 months after buccal ureteroplasty.

RESULTS: The experimental part of the study demonstrated the possibility and effectiveness of ureteroplasty with a buccal graft, and also revealed the restructuring of squamous epithelium into transitional cell. In patients 12 and 24 months after buccal ureteroplasty similar changes in the mucous membrane of the graft were not observed, therefore, further study of the mucous membrane of the buccal graft in later postoperative periods is necessary.

CONCLUSIONS: The results of experimental and clinical studies indicate the possibility of using a graft from the buccal mucosa for plastic surgery of extensive and recurrent ureteral strictures. Unlike animals, where a restructuring of squamous to transitional cell epithelium was observed, similar morphological changes did not occur in patients after buccal ureteroplasty.

Urology reports (St. - Petersburg). 2023;13(4):315-322
pages 315-322 views
Prognostic value of immunological components of tumor microenvironment of oncourological tumors
Molchanov O.E., Maistrenko D.N., Granov D.A., Shkolnik M.I., Lisitsyn I.Y., Belov A.D., Kneev A.Y.
Abstract

BACKGROUND: In the last decade, the tumor microenvironment has been considered as one of the key factors determining the prognosis and nature of the necessary therapeutic interventions. Currently, there is only one validated and approved predictive model that includes microenvironment components. Several classifications of the tumor microenvironment based on the nature of the predominant cellular subpopulations have been proposed.

AIM: The aim of the study was to assess the prognostic significance of the immunological components of blood and the microenvironment, as well as to create prognostic models for oncourological tumors.

MATERIALS AND METHODS: The study used clinical data from 115 patients with kidney, bladder and prostate cancer. Immunological parameters in the tumor and blood microenvironment were evaluated in all patients. The end point of observation was the median time to progression. The influence of various parameters on long-term treatment outcomes was evaluated using the log rank and the Gehan–Wilcoxon criteria. A model of proportional hazard was used to identify the combined effect of several parameters on lifetime indicators.

RESULTS: The developed prognostic models for all studied groups include spontaneous production of three cytokines: IL-6, IL-8 and IL-10. The prognostic models for renal cell carcinoma and prostate cancer also included immunosuppressive components: MDSC and Treg. The median time to progression in patients with invasive urothelial cancer is influenced by components that contribute to tumor destruction: TNK cells and IFN-γ. In all the studied groups of patients (renal cell carcinoma, muscle-invasive urothelial cancer, prostate cancer), the median time to progression significantly differs in subgroups with different numbers of immunological risk factors for tumor microenvironment.

CONCLUSIONS: The developed prognostic models are based on modern achievements of oncoimmunology and after conducting multicenter validation studies, they can be recommended for clinical use.

Urology reports (St. - Petersburg). 2023;13(4):323-337
pages 323-337 views
Clinical significance of the use of intraoperative ultrasound dopplerography during Marmar surgery
Lankov V.A., Borovets S.Y., Nevirovich E.S., Al-Shukri S.K.
Abstract

BACKGROUND: Intraoperative ultrasound Dopplerography is rarely used to facilitate the recognition and dissection of vascular structures during Marmar surgery.

AIM: The aim of the study is to compare the effectiveness of restoring the fertile properties of the ejaculate and the frequency of complications after Marmar surgery with and without intraoperative Doppler in patients with clinically significant varicocele and male infertility factor.

MATERIALS AND METHODS: The study included 96 men with a diagnosis of left-sided varicocele. The patients were divided into two groups. The group 1 included 41 patients who underwent Marmar surgery with intraoperative Doppler, and the group 2 included 55 patients but without the use of dopplerography. All patients were examined before the operation and three and six months after.

RESULTS: In the group 1 of patients, a more significant increase in the concentration and number of progressively mobile forms of sperm was noted three and six months after surgery, compared with similar indicators in patients of the group 2 (р < 0.05). The use of intraoperative Doppler significantly reduced the time of surgical intervention, the frequency of complications and relapses, the detection of venous and arterial vessels (р < 0.05). After Marmar surgery using intraoperative Doppler, there were no complications and relapses observed during six months of follow-up.

CONCLUSIONS: 1. Intraoperative Doppler control allows ligating a larger number of venous trunks and preserving a larger number of arteries in the spermatic cord during the Marmar surgery, thereby reducing the time of surgical intervention, preventing the development of relapses and complications of the disease. 2. The use of intraoperative Doppler during the Marmar surgery leads to a more significant increase in the concentration and number of progressively motile sperm forms both three and six months after the operation compared to the classical technique.

Urology reports (St. - Petersburg). 2023;13(4):339-346
pages 339-346 views
Intraoperative application of photodynamic therapy as a method of inactivation of uropathogenic flora (pilot study)
Streltsova O.S., Antonian A.E., Elagin V.V., Ignatova N.I., Yunusovа K.E., Zhilyaeva-Fomina T.R., Lazukin V.F., Kamensky V.A.
Abstract

BACKGROUND: The predictor of experimental work on animals on the use of antimicrobial photodynamic therapy to neutralize antibiotic-resistant strains of microorganisms was the analysis of the microbial landscape of patients’ urine and swabbings from the working surfaces of objects of the urological hospital.

AIM: The aim of the study is was to study the possibility of intraoperative photodynamic inactivation of uropathogenic microorganisms.

MATERIALS AND METHODS: Analysis of the species specificity of microorganisms was performed based on the results of urine cultures of patients in a urological hospital and external introduction infections over the past 10 years. The experimental part of the work was carried out on 7 animals (pigs). Photodynamic therapy was performed intraoperatively by local injection into the animals’ renal pelvis of the photosensitizer photoditazine in physiological solution with the addition of the nonionic surfactant Triton X-100 to a concentration of 10%. To study the damaging effect on the tissue of the pelvis, a histological study of animal kidneys was performed. To assess the biocidal effect on uropathogenic bacteria introduced into the renal pelvis, we used suspensions of daily test cultures (1 × 108 CFU/ml) of microorganisms most often found in the stones of patients with urolithiasis.

RESULTS: Escherichia coli, Enterobacter cloacae, Staphylococcus epidermidis, Enterococcus faecalis и Klebsiella pneumonia were the most frequently present in urine over 10 years. The safety of using photodynamic therapy in the renal pelvis of animals was comprehensively studied. It was found that the accumulation of the photosensitizer by the cells of the lining epithelium of the renal pelvis did not occur; the photosensitizer solution in the renal pelvis was not heated during photodynamic therapy. Histological examination established the absence of significant damage to the epithelium of the renal pelvis of the animals under the influence of various irradiation modes. The analysis of the bactericidal activity of the method used showed that photodynamic therapy leads to the death of 99.9% of E. coli and 99% of S. aureus.

CONCLUSIONS: The experiment established that intraoperative photodynamic therapy is an effective and safe method of inactivating uropathogenic microorganisms, which allows it to be considered as an alternative to antibiotic therapy.

Urology reports (St. - Petersburg). 2023;13(4):347-357
pages 347-357 views
Intraperitoneal perforations of the bladder in pediatric urological practice. Comparative evaluation of the effectiveness of various therapeutic and diagnostic approaches
Shchedrov D.N., Shormanov I.S., Logval A.A., Morozov E.V., Garova D.Y., Sidorova N.A.
Abstract

BACKGROUND: Intraperitoneal damage to the bladder in the pediatric population is a rare phenomenon. Publications describe small series of observations, generalizing studies are isolated. There are no uniform diagnostic algorithms and tactics of patient management, a large number of diagnostic and tactical errors.

AIM: The aim of this study is to evaluate the possibilities of laparoscopy in the diagnosis and treatment of patients under 18 years of age with intraperitoneal bladder injuries.

MATERIALS AND METHODS: The work was based on the results of treatment of 16 patients with intraperitoneal perforations of the bladder under the age of 18, who were in the Regional Pediatric Clinical Hospital (Yaroslavl) and Vologda Regional Children’s Hospital No.2 (Cherepovets) for the period 2003–2023. In 10 cases, the perforations were traumatic in nature, in 6 — iatrogenic in nature.

RESULTS: Surgical treatment was performed with traditional access in 6 cases, laparoscopic — in 10. The groups of patients are similar in clinical parameters. Laparotomic surgical intervention was performed from the lower median access (n = 4) and Pfanenstiel access (n = 2); with laparoscopic intervention (n = 10), a trocar arrangement with umbilical access for the camera and two accesses in the iliac regions for instruments was used. Laparoscopic surgery was accompanied by less blood loss. The duration of bladder drainage with laparoscopic intervention is reduced by 1.7 days. Laparoscopic surgery in 1 case was accompanied by the installation of a cystostomy, in the rest drainage was carried out by catheterization of the bladder. Open surgery was mainly completed by performing a cystostomy or combined drainage with a cystostomy and a urethral catheter. The duration of hospitalization is significantly shorter after laparoscopic intervention. In the first 10 years (2002–2012) 5 open operations and 2 laparoscopic operations were performed, and in the second 10 years (2013–2023) — 8 laparoscopic and one open operations. The tactics regarding bladder drainage are changing: in the first analyzed period, drainage was carried out mainly by cystostomy (n = 5) and less often by urethral catheter (n = 2), subsequently — mainly by urethral catheter (n = 7), less often by cystostomy (n = 1) or by simultaneous drainage by stoma and catheter (n = 1).

CONCLUSIONS: Laparoscopic suturing is the method of choice in all cases of isolated intraperitoneal perforations of the bladder and in most combined injuries. Indications for open intervention are combined abdominal injuries, active intra-abdominal bleeding. The urethral catheter has advantages over cystostomy.

Urology reports (St. - Petersburg). 2023;13(4):359-367
pages 359-367 views
Advantages and disadvantages of percutaneous surgery of urolithiasis in the patient’s supine position
Suleymanov S.I., Kadyrov Z.A., Aguzarov A.M., Ashurov Z.I., Babkin A.S., Bagaturiya K.K., Musohranov V.V., Tyagun A.A., Fedorov D.A.
Abstract

BACKGROUND: Studying the clinical features of different surgical approaches in patients with urolithiasis with stones localized in the kidney and the upper third of the ureter is an important practical issue in modern urology.

AIM: The aim of the study is a clinical evaluation of the results of percutaneous surgery for urolithiasis with the patient in the supine position.

MATERIALS AND METHODS: The results of surgical treatment of 316 patients with urolithiasis with stones localized in the kidney (more than 10 mm) and the upper third of the ureter (more than 8 mm) are presented. All patients underwent percutaneous nephrolithotripsy in the supine position.

RESULTS: Complete elimination of stones was achieved in 91.3% of patients with stones of the upper third of the ureter and 96.2% of patients with kidney stones. Clinical evaluation of the surgical results showed that the frequency of intraoperative complications of traumatic origin is about 10%, the most common complication being bleeding. At the same time, complications of grades IV and V according to the Clavien–Dindo classification were noted. Performing percutaneous nephrolithotripsy in the supine position reduces the time required to position the patient, allows for the combination of transurethral and percutaneous interventions, is more effective for patients with increased weight and concomitant diseases, and also provides a significant advantage in the need for ventilation and possible resuscitation.

CONCLUSIONS: It is advisable to introduce a personalized approach to the choice of surgical access when performing invasive interventions on the upper urinary tract.

Urology reports (St. - Petersburg). 2023;13(4):369-376
pages 369-376 views
A novel device for aspiration and irrigation in endovideosurgery: flexible head for aspirator-irrigator with memory effect
Mosoyan M.S., Shelipanov D.A., Fedorov D.A., Gilev E.S., Vasilev A.A.
Abstract

BACKGROUND: Aspiration of biological fluids, including blood and urine, as well as irrigation of the surgical field are important tasks at any stage of the majority of abdominal surgical interventions. These functions are necessary to prevent contamination of the abdominal cavity, clean the surgical field from fluid accumulations and blood clots, which in turn allows for optimal visualization for the operating surgeon. During endovideosurgical partial nephrectomy, maintaining a clean surgical field and adequate visualization of the resection area is often a difficult task, especially with posterior tumors. This is due to difficulties in reaching the resection zone due to insufficient instrument length and/or instrument bending.

AIM: The aim of the study is to study the properties of a new flexible nozzle for an aspirator-irrigator during kidney resection on a model of the intraabdominal space using a pig organ complex.

MATERIALS AND METHODS: The nozzle for the aspirator-irrigator is made of polyvinyl chloride, has the shape of a straight hollow tube 80 mm long and 6.5 mm in diameter; on the inner side surfaces there are two channels with a diameter of 1 mm, in which brass rods are located, giving the structure rigidity, with the possibility of changing it forms with a “memory effect”. This nozzle is attached to the distal end of a standard metal tube of the aspirator-irrigator, after which the surgeon gives it the necessary bend, sufficient to penetrate into hard-to-reach areas of the surgical field. Using a pig organ complex and a laparoscopic simulator, a model of the abdominal cavity and retroperitoneal space was created. Laparoscopic instruments were used to simulate an endovideosurgical operation. Using laparoscopic scissors, a wedge-shaped resection of a section of the renal parenchyma (with a suspected tumor) was performed. Aspiration tubes were brought to the formed parenchymal defect — first a standard straight metal tube, then an aspiration tube with a flexible tip, which was previously given the necessary bend. At the end of the experiment, the effectiveness of using the new device in conditions of hard-to-reach localization of the resection zone, its safety for surrounding tissues and organs, as well as its convenience for the surgeon were assessed.

RESULTS: The effectiveness of the new attachment for resection of a suspected posterior renal tumor in a simulated intraabdominal space using a porcine organ complex. The access, aspiration, and irrigation were difficult and took longer time with using of the standard aspirator-irrigator tip, than with the new flexible tip.

CONCLUSIONS: The new flexible aspirator-irrigator head provides safe and rapid access to difficult-to-reach partial nephrectomy sites, as well as efficient aspiration and irrigation.

Urology reports (St. - Petersburg). 2023;13(4):377-382
pages 377-382 views
Comparative evaluation of the results of two-stage abdominal testicle reduction by Fowler–Stephens and a one-stage method with preservation of testicular vessels
Kagantsov I.M., Logval A.A.
Abstract

BACKGROUND: Normal testicular function is only possible if it is located in the scrotum; if the testicle is undescended, fertility decreases and the risk of malignancy increases.

AIM: Aim of the study is to compare the results of a one-stage bringing down of the abdominal testicle with preservation of the testicular vessels and a two-stage Fowler–Stephens operation regarding the risk of atrophy of the reduced gonad.

MATERIALS AND METHODS: A total of 241 patients with a non-palpable testicle in the scrotum were observed, of which 125 (51.87%) patients the testicles were brought down with laparoscopic assistance. Three groups of patients were identified. The first group consisted of 105 (84%) patients who underwent testicular bringing down in two stages using the Fowler–Stephens technique with an interval of at least 6 months. The second group consisted of 20 (16%) patients whose underwent laparoscopic bringing down in one stage with preservation of the testicular vessels. The main criterion for effectiveness was the size of the gonad 6 months after surgery according to ultrasound. The third group included 116 (48.13%) patients with absent testicle.

RESULTS: In the first group the average duration of the first stage of the operation was 19.07 [10; 65] minutes, second stage 48.59 [20; 160] minutes. A total of 117 testicles were brought down to the scrotum. 77 (65.81%) hypoplastic gonads were identified, of which in 6 (5.13%) cases the volume of the testicle increased after the first stage of the operation, 8 (6.84%) gonads decreased in volume and 1 (0.85%) testicle atrophied after completing the second stage. In 62 (52.30%) testicles the size did not change between the stages of the operation. Subsequently, these gonads remained hypoplastic. In 40 (34.19%) gonads there was no decrease in volume, but between the stages of intervention, an increase in the volume of the organ was noted in 3 (2.56%) cases, in 7 (5.98%) cases a decrease in the volume of the gonads, in 29 (24.79%) of patients, the size of the testicles did not change between the stages of the operation, 1 (0.85%) of the gonad atrophied after the second stage of the operation. In the second group the average duration of the operation was 42.59 [20; 100] minutes. A total of 22 gonads were brought down, of which 6 (27.27%) testicles were not hypoplastic and did not decrease in size after being brought down into the scrotum, 16 (72.73%) — were initially hypoplastic. Of these, 1 (4.55%) gonad increased in volume, 1 (4.55%) — decreased, 14 (63.64%) — remained unchanged after surgery. There was no testicular atrophy after descent. In patients of the third group, in 40 (34.48%) cases, the vessels ended blindly in the abdominal cavity. In 3 (2.59%) boys, testicular buds located in the abdominal cavity were removed. The vessels of the testicle went into the inguinal canal in 73 (62.93%) cases, of which in 34 (29.31%) — the vessels ended blindly and 39 (33.62%) testicular rudiments were found, which were removed.

CONCLUSIONS: Bringing down of the testicle with preservation of its own vessels is more preferable compared to a two-stage operation due to the absence of the need for a second intervention on the gonad, a greater degree of preservation of testicular volume after its brought down and, in our case, the absence of gonadal atrophy after its descending.

Urology reports (St. - Petersburg). 2023;13(4):383-389
pages 383-389 views

Reviews

Arterial embolization in the treatment of benign and malignant prostate lesions
Golovataya A.D., Gorelov V.P., Sharafutdinov E.F., Suvorova J.V., Gorelov S.I.
Abstract

Prostatic artery embolization is an X-ray endovascular method for treating patients with lower urinary tract symptoms due to prostate diseases. Over the past 10 years, interest in this problem has grown significantly, as can be judged by the increase in the number and scale of research on this topic. The review article provides information about the effectiveness of this treatment method for benign and malignant prostate tumors. The search for information sources was carried out using the PubMed and eLibrary.ru databases. Key words used are “embolization of prostatic arteries”, “chemoembolization of prostate cancer”, “prostate cancer”, “benign prostatic hyperplasia”, “lower urinary tract symptoms” (in Russian and English). The prospects for embolization of prostatic arteries in urological and oncological practices and the need for more large-scale research in this direction are noted.

Urology reports (St. - Petersburg). 2023;13(4):391-400
pages 391-400 views

Сlinical observations

Renal pelvis cancer — 6 years without treatment and metastasis (case report)
Zamyatnin S.A., Gonchar I.S., Kosarev A.V.
Abstract

Renal pelvis cancer is a rare cancer. The data presented in the literature indicate that timely diagnosis and early surgical treatment, often in combination with chemotherapy and radiation therapy, are the key to success. This is due to the high metastatic potential of this type of tumor, rapid spread to the bladder and, as a consequence, unsatisfactory long-term results. This paper presents a rare case of papillary cancer of the renal pelvis, which has completely spread throughout the lumen of the left ureter and into the cavity of the bladder. The duration of the disease in the absence of regional and distant metastasis is surprising. For the first time, the dynamics of tumor tissue growth from the pelvis to the bladder over 3 years in the absence of treatment is presented using a clinical example.

Urology reports (St. - Petersburg). 2023;13(4):401-407
pages 401-407 views


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies