Clinical aspects of the applicability of biomarkers of acute kidney injury in ischemia-reperfusion in operative urology

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详细

The development of acute kidney injury during surgical renal-preserving interventions characterizes the nature of the clinical course and prognosis for the development of chronic kidney disease. The use of standard indicators of disease progression (serum creatinine and urea nitrogen) in clinical practice can lead to unfavorable outcomes of acute kidney injury due to their low sensitivity and high specificity against the background of damage to more than 50% of the renal parenchyma). Other biomarkers of acute kidney injury (cystatin C, IL-18, KIM-1, NGAL, L-FABP, NAG and others) are superior to creatinine in sensitivity and specificity, but require additional research to identify the most optimal ones for clinical practice.

作者简介

Sergey Popov

Clinical Hospital of St. Luke; Saint Petersburg Medical and Social Institute; Kirov Military Medical Academy

Email: doc.popov@gmail.com
ORCID iD: 0000-0003-2767-7153
SPIN 代码: 3830-9539
Scopus 作者 ID: 57197368945

MD, Dr. Sci. (Medicine), Professor

俄罗斯联邦, Saint Petersburg; Saint Petersburg; Saint Petersburg

Ruslan Guseinov

Clinical Hospital of St. Luke; Saint Petersburg Medical and Social Institute; Saint Petersburg State University

Email: rusfa@yandex.ru
ORCID iD: 0000-0001-9935-0243
SPIN 代码: 4222-4601
Scopus 作者 ID: 57209859097

MD, Cand. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg; Saint Petersburg; Saint Petersburg

Konstantin Sivak

Clinical Hospital of St. Luke; Smorodintsev Research Institute of Influenza

Email: kvsivak@gmail.com
ORCID iD: 0000-0003-4064-5033
SPIN 代码: 7426-8322
Scopus 作者 ID: 35269910300

Dr. Sci. (Biology)

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Vitaliy Perepelitsa

Clinical Hospital of St. Luke; Saint Petersburg Medical and Social Institute

Email: perepelitsa_vit@mail.ru
ORCID iD: 0000-0002-7656-4473
SPIN 代码: 7445-1996
Scopus 作者 ID: 14823999900

MD, Cand. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg; Saint Petersburg

Nikolai Bunenkov

Clinical Hospital of St. Luke; Almazov National Medical Research Centre; Academician I.P. Pavlov First Saint Petersburg State Medical University

Email: bunenkov2006@gmail.com
ORCID iD: 0000-0003-4331-028X
SPIN 代码: 3611-1290
Scopus 作者 ID: 57191173503

MD, Cand. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg; Saint Petersburg; Saint Petersburg

Tatiana Lelyavina

Clinical Hospital of St. Luke; Almazov National Medical Research Centre

编辑信件的主要联系方式.
Email: tatianalelyavina@mail.com
ORCID iD: 0000-0002-1834-4982

MD, Dr. Sci. (Medicine)

俄罗斯联邦, Saint Petersburg; Saint Petersburg

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