Email this article Differential diagnosis of thrombocytosis: a case study
- Authors: Budai A.P.1, Ermolov S.Y.1, Dobritca V.P.1, Ilyashevich I.G.1, Apresyan A.G.1
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Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- Issue: Vol 15, No 2 (2023)
- Pages: 87-92
- Section: Case report
- Submitted: 14.04.2023
- Accepted: 14.05.2023
- Published: 28.07.2023
- URL: https://journals.eco-vector.com/vszgmu/article/view/326388
- DOI: https://doi.org/10.17816/mechnikov326388
- ID: 326388
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Abstract
The article presents a clinical case of an unclassifiable myeloproliferative neoplasm in a 65-year old patient. Platelet count is not a criteria for differential diagnosis of reactive and tumor processes. A typical course of the disease is associated with the persistence of symptoms of microcirculation disorder against the background of previous asymptomic thrombocytosis for several years. The diagnosis of an unclassifiable myeloproliferative neoplasm is established by a combination of clinical, laboratory, instrumental, molecular genetic and morphological methods of research.
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About the authors
Aleg P. Budai
North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: aleg.buday@mail.ru
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Sergei Yu. Ermolov
North-Western State Medical University named after I.I. Mechnikov
Email: s.j.ermolov@mail.ru
ORCID iD: 0000-0002-7053-1478
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgValerii P. Dobritca
North-Western State Medical University named after I.I. Mechnikov
Email: valeriy-pav-dobritsa@yandex.ru
ORCID iD: 0000-0003-2767-936X
SPIN-code: 7386-3984
MD, Dr. Sci. (Med.), Professor
Russian Federation, Saint PetersburgInna G. Ilyashevich
North-Western State Medical University named after I.I. Mechnikov
Email: Inna.Ilyashevich@szgmu.ru
ORCID iD: 0000-0002-5784-2634
SPIN-code: 3212-7518
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, Saint PetersburgAnna G. Apresyan
North-Western State Medical University named after I.I. Mechnikov
Email: anna.apresyan@szgmu.ru
ORCID iD: 0000-0003-0637-9384
SPIN-code: 8654-7705
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, Saint PetersburgReferences
- Melikyan AL, Kovrigina AM, Subortseva IN, et al. National clinical guidelines for the diagnosis and treatment of Ph-negative myeloproliferative diseases (polycythemia vera, essential thrombocythemia, primary myelofibrosis) (Edition 2020). Clinical oncohematology. 2021;14(2):264–298. (In Russ.)
- Abdulkadyrov KM, Shuvaev VA, Martynkevich IS, et al. Modern concept of diagnosis and management of essential thrombocytemia. Bulletin of Hematology. 2014;10(1):4–33. (In Russ.)
- Bogdanov AN, Tyrenko VV, Noskov YA, Semelev VN. Differentsial’naya diagnostika trombotsitozov v klinicheskoi praktike. Bulletin of the Russian Military Medical Academy. 2014;46(2):44–50. (In Russ.)
- Sokolova NA. Differentsial’naya diagnostika trombotsitozov. In: Gematologicheskie issledovaniya i laboratornoe obespechenie transfuziologii (prakticheskoe posobie). 2015. P. 2–15.
- Mikhailova ZD, Cherepanova VV. Thrombocytoses in the practice of nephrology as the cause of thrombohemorrhagic complications. Clinical nephrology. 2021;3:61–65. (In Russ.) doi: 10.18565/nephrology.2021.3.61-65
- Bagrova IV, Kukharchik GA, Serebryakova VI, et al. Modern approaches to the diagnosis of pulmonary embolism. Phlebology. 2012;6(4):35–42. (In Russ.)
- Skoda RC. Thrombocytosis. ASH Education program book. 2009:(1):159–167.
- Vannucchi AM, Barbui T. Thombocytosis and thrombosis. ASH Education program book. 2007;1:363–370.
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