Email this article Systemic transtiretin amyloidosis in the elderly patient with recurrent pleural effusions
- Authors: Boldueva S.A.1, Evdokimov D.S.1, Shvets N.S.1, Shahbazyan A.V.1, Kalinina E.Y.2, Mitrofanova L.B.3
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Affiliations:
- North-Western State Medical University named after I.I. Mechnikov
- Saint-Petersburg State Pediatric Medical University
- Almazov National Medical Research Centre
- Issue: Vol 13, No 3 (2021)
- Pages: 91-98
- Section: Case report
- Submitted: 04.09.2021
- Accepted: 05.11.2021
- Published: 15.10.2021
- URL: https://journals.eco-vector.com/vszgmu/article/view/79512
- DOI: https://doi.org/10.17816/mechnikov79512
- ID: 79512
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Abstract
Systemic amyloidosis is a group of diseases associated with extracellular deposition of fibrillar proteins, which leads to a loss of normal organ structure and function. Transthyretin amyloidosis occurs with the deposition of amyloid, consisting of transthyretin transport protein, and can be a genetic or degenerative disease of senility (acquired from the deposition of wild-type transthyretin).
The article describes the clinical case of transthyretine amyloidosis in elderly patient, manifested by recurrent pleural effusions and biventricular heart failure demonstrating the complexity of timely diagnosis of wild-type transthyretin amyloidosis.
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About the authors
Svetlana A. Boldueva
North-Western State Medical University named after I.I. Mechnikov
Email: svetlanaboldueva@mail.ru
ORCID iD: 0000-0002-1898-084X
Scopus Author ID: 6506877971
MD, Dr. Sci. (Med.), Professor
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Dmitriy S. Evdokimov
North-Western State Medical University named after I.I. Mechnikov
Author for correspondence.
Email: kasabian244@gmail.com
ORCID iD: 0000-0002-3107-1691
аспирант кафедры факультетской терапии
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Natalia S. Shvets
North-Western State Medical University named after I.I. Mechnikov
Email: natashashvets@yandex.ru
MD, Cand. Sci. (Med.)
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Anahit V. Shahbazyan
North-Western State Medical University named after I.I. Mechnikov
Email: shahbazyananahit13@gmail.com
ORCID iD: 0000-0002-6923-5321
врач-кардиолог
Russian Federation, 41 Kirochnaya St., Saint Petersburg, 191015Elena Yu. Kalinina
Saint-Petersburg State Pediatric Medical University
Email: drkalinina@yandex.ru
MD, Cand. Sci. (Med.)
Russian Federation, Saint PetersburgLyubov B. Mitrofanova
Almazov National Medical Research Centre
Email: lubamitr@yandex.ru
MD, Dr. Sci. (Med.), Assistant Professor
Russian Federation, Saint PetersburgReferences
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