On the use of antiseptics in clinical practice
- Authors: Isaev Y.A.1, Belyak M.A.1
-
Affiliations:
- Tver State Medical University of the Ministry of Health of the Russian Federation
- Issue: Vol 26, No 2 (2024)
- Pages: 33-35
- Section: Profession: theory and practice
- URL: https://journals.eco-vector.com/0025-8342/article/view/629539
- DOI: https://doi.org/10.29296/25879979-2024-02-07
- ID: 629539
Cite item
Open Access
Access granted
Abstract
To address the spread of pathogenic agents and minimize the risk of infection, it is essential to apply measures for proper antiseptic treatment of the surgical site prior to an invasive medical procedure to effectively reduce the incidence of surgical site infection and associated complications. Knowledge of the concepts and standards for the use of antiseptic and disinfectant agents helps health care providers to effectively prevent the spread of infectious agents and provides a scientific basis for their rational use. Research on the mechanisms of action of antiseptics has not only scientific but also practical importance for nurses and clinicians, which is related to more effective use of these drugs in professional activities and potential development of new promising compounds and their combinations.
Keywords
Full Text
About the authors
Yuri A. Isaev
Tver State Medical University of the Ministry of Health of the Russian Federation
Author for correspondence.
Email: iura.isaew2015@yandex.ru
ORCID iD: 0000-0002-9657-8063
Candidate of Medical Sciences, Associate Professor of the Department of General Surgery
Russian Federation, TverMaria A. Belyak
Tver State Medical University of the Ministry of Health of the Russian Federation
Email: iura.isaew2015@yandex.ru
ORCID iD: 0000-0001-6125-7676
student
Russian Federation, TverReferences
- Morozov A.M., Sergeev A.N., Sergeev N.A. et al. Diagnostics and prophylaxis of infectious complications of the area of surgical intervention. Bulletin of Ivanovo Medical Academy. 2021; 26 (1): 54‒58. doi: 10.52246/1606-8157-2021-26-1-54
- Morozov A.M., Zhukov S.V., Belyak M.A., et al. Evaluation of economic losses due to the development of surgical site infection. Health Care Manager. 2022; (1): 54-60. doi: 10.21045/1811-0185-2022-1-54-60
- Boisson M., Corbi P., Kerforne T. et al. Multicentre, open-label, randomized, controlled clinical trial comparing 2% chlorhexidine-70% isopropanol and 5% povidone iodine-69% ethanol for skin antisepsis in reducing surgical-site infection after cardiac surgery: the CLEAN 2 study protocol. BMJ Open. 2019; 9 (6): e026929.
- Musaev A.I., Isaev E.B., Maksut E., et al. Infection control in high-risk wards. Economic significance of infection in surgical intervention. Bulletin of the Kyrgyz State Medical Academy named after I.K. Akhunbaev. 2018; (2): 58‒63.
- Certificate of state registration of the database №2022620494 Russian Federation. Database of educational and methodical materials on the topic «Infection of the area of surgical intervention»: №2022620343: avv. 22.02.2022: published 14.03.2022 / M.A. Belyak, K.V. Bukanova, E.V. Bulanova et al.
- Gallo R.L. Human skin is the largest epithelial surface for interaction with microbes. J Invest Dermatol 2017; 137 (6): 1213‒1214.
- Sandle T. Standards and controls for skin disinfection. Clin Serv J. 2016; 15 (2): 25–28.
- Morozov A.M., Sergeev A.N., Kadykov V.A. et al. Modern antiseptic agents in the treatment of the surgical field. Bulletin of modern clinical medicine. 2020; 13 (3): 51–58. doi: 10.20969/VSKM.2020.13(3).51-58.39.
- Certificate of state registration of the database №2022620561 Russian Federation. Database of educational and methodical materials on the topic «Asepsis and antisepsis»: №2022620323: avv. 22.02.2022: publ. 16.03.2022 / M.A. Belyak, K.V. Bukanova, E.V. Bulanova et al. doi: 10.25881/BPNMSC.2020.61.32.023
- Gataullin B.F., Galimullina E.I. Antibacterial agents for surface protection. Goals and ways of sustainable economic development: A collection of articles based on the materials of the international scientific and practical conference, Ufa, January 28, 2020. Ufa: Limited Liability Company «Scientific Publishing Center «Bulletin of Science», 2020; p. 20-25.
- Zemlyanoi A.B., Afinogenova A.G., Matveev S.A. The use of antiseptics in the treatment of wounds with a high risk of infection. Bulletin of the National Medical and Surgical Center named after N.I. Pirogov. 2020; 15 (2): 129‒137. doi: 10.25881/BPNMSC.2020.61.32.023
- Maillard J.Y., Pascoe M. Disinfectants and antiseptics: mechanisms of action and resistance. Nat Rev Microbiol. 2024; 22 (1): 4‒17. doi: 10.1038/s41579-023-00958-3
- Chernyakov A.V. Modern antiseptics and surgical aspects of their use. RMZH. 2017; 25 (28): 2059‒2062.
- Melnikova O.A. Comparative analysis of different chemical groups of skin antiseptics. Nursing. 2019; (10): 18‒22. doi: 10.33920/med-05-1910-05;616-089
- Putilina A.D., Kamenkova T.S., Zaitseva E.A. Modern ideas about the mechanisms of formation of resistance of microorganisms to antimicrobial drugs. Pulse Medical and Pharmaceutical journal. 2019; 10: 125‒130. doi: 10.26787/nydha-2686-6838-2019-21-10-125-130
- Sosnovskikh Ya. I., Timoshenko A.N. Bacterial resistance to antiseptics and disinfectants. Actual medicine: materials of the I Student scientific-theoretical conference dedicated to the 120th anniversary of the birth of S. I. Georgievsky, Simferopol, November 29, 2018. Simferopol: Crimean Federal University named after V. I. Vernadsky. V.I. Vernadsky, 2018; 349‒354.
- Josep M. Badia, Anna L. Casey, Inés Rubio-Pérez et al. A survey to identify the gap between evidence and practice in the prevention of surgical infection: Time to take action, International Journal of Surgery. 2018; 54 (A): 290‒297.
- Kalingamudali Y.T., Jalini P., Jayamaha A. et al. Knowledge, attitudes, and practices on the usage of antiseptics prior to invasive medical procedures: Evidence from Sri Lankan Healthcare Professionals. SAGE Open Med. 2023; 11: 20503121231199654. doi: 10.1177/20503121231199654
- Vila Dominguez A., Ayerbe Algaba R., Miro Canturri A. et al. Antibacterial activity of colloidal silver against gram-negative and gram-positive bacteria. Antibiotics (Basel). 2020; 9 (1): 36.
- Liao S., Zhang Y., Pan X., et al. Antibacterial activity and mechanism of silver nanoparticles against multidrug-resistant Pseudomonas aeruginosa. Int J Nanomedicine. 2019; 14: 1469‒1487.
- Jung W.K., Koo H.C., Kim K.W. et al. Antibacterial activity and mechanism of action of the silver ion in Staphylococcus aureus and Escherichia coli. Appl. Environ. Microbiol. 2008; 74: 2171‒2178. doi: 10.1128/AEM.02001-07
- Privolnev V.V., Zabrosaev V.S., Danilenkov N.V. Silver preparations in local treatment of infected wounds. Bulletin of Smolensk State Medical Academy. 2015; 14 (3): 85‒91.
- Shinzato Y., Sakihara E., Kishihara Y. et al. Clinical application of skin antisepsis using aqueous olanexidine: a scoping review. Acute Med Surg. 2022; 9 (1): e723. doi: 10.1002/ams2.723.
- Morozov A.M., Sergeev A.N., Dubatolov G.A., et al. Modern means for the treatment of surgeon’s hands and surgical field (literature review). Disinfection. 2020; 4 (114): 41‒50. doi: 10.35411/2076-457X-2020-4-41-50
- Nakaminami H., Takadama S., Okita M. et al. Fast-acting bactericidal activity of olanexidine gluconate against qacA/B-positive methicillin-resistant Staphylococcus aureus. J. Med. Microbiol. 2019; 68: 957-960.
- Seyama S., Nishioka H., Nakaminami H. et al. Evaluation of in vitro bactericidal activity of 1.5% olanexidine gluconate, a novel biguanide antiseptic agent. Biol. Pharm. Bull. 2019; 42: 512‒515.
Supplementary files
