Joint damage among the patients with COVID-19 in nurse practice
- Authors: Skvortsov V.V.1, Matokhin S.E.1, Akimochkin G.S.1, Karchevsky A.A.1
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Affiliations:
- FSBEI НЕ VolgSMU МОН Russia
- Issue: Vol 26, No 4 (2024)
- Pages: 53-56
- Section: Profession: theory and practice
- URL: https://journals.eco-vector.com/0025-8342/article/view/633546
- DOI: https://doi.org/10.29296/25879979-2024-04-10
- ID: 633546
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Abstract
Rheumatoid pathology of the articular apparatus is a significant social problem due to the high incidence of disability. Cases of the development of arthropathy after SARS-CoV-2 infection have been described. The basis of the pathogenesis of this condition may be the excessive synthesis of pro-inflammatory cytokines (cytokine storm), which is characteristic of the acute course of COVID-19. In patients with a severe form of coronavirus infection, a high concentration of a number of cytokines was observed: IFN-γ, IL-1, IL-6, IL-12, TGFβ. Due to the activation of osteoclasts, resorptive processes in bone tissue were significantly enhanced. Autoimmunization due to cross-reactivity of the virus can also lead to joint damage. Reactive arthritis tends to be acute, occurs in the form of monoarthritis or oligoarthritis. The pathological process develops mainly in the joints of the wrist, ankles and small joints of the distal parts of the arms and legs.
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About the authors
Vsevolod V. Skvortsov
FSBEI НЕ VolgSMU МОН Russia
Author for correspondence.
Email: vskvortsov1@ya.ru
ORCID iD: 0000-0002-2164-3537
Doctor of Medicine, Associate Professor of the Department of Internal Medicine
Russian Federation, VolgogradSergey E. Matokhin
FSBEI НЕ VolgSMU МОН Russia
Email: sergo.mat-n@yandex.ru
4th Year Student of Faculty of General Medicine
Russian Federation, VolgogradGavriil S. Akimochkin
FSBEI НЕ VolgSMU МОН Russia
Email: gavriil.akimochkin@mail.ru
4th Year Student of Faculty of General Medicine
Russian Federation, VolgogradAlexander A. Karchevsky
FSBEI НЕ VolgSMU МОН Russia
Email: 566aak225@mail.ru
1st Year Student of Faculty of General Medicine
Russian Federation, VolgogradReferences
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