Role of risk factors in the development of cholelithiasis

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Abstract

Biliary stone disease is currently one of the most common nosologies, and its social significance has increased significantly in recent years. Gallstone disease is mainly caused by the following factors: bile cholesterol oversaturation caused by excessive cholesterol secretion in the liver due to genetic factors; systolic dysfunction of the gallbladder wall; intestinal dysfunction with excessive cholesterol absorption or increased blood cholesterol content caused by impaired hepatic circulation of bile; and accelerated growth of cholesterol crystals. To prevent the development of this pathology, it is necessary to observe the measures of primary prevention, including the refusal of bad habits, adherence to a balanced diet with a predominance of plant foods to normalize and maintain the motility of the gastrointestinal tract.

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About the authors

Artem Mikhailovich Morozov

Tver State Medical University

Author for correspondence.
Email: ammorozovv@gmail.com
ORCID iD: 0000-0003-4213-5379
SPIN-code: 6815-9332

Candidate of Medical Sciences, Associate Professor of the Department of General Surgery

Russian Federation, Tver

Maria D. Buinova

Tver State Medical University

Email: ammorozovv@gmail.com
ORCID iD: 0009-0003-5126-5316

student

Russian Federation, Tver

Anastasia V. Titova

Tver State Medical University

Email: ammorozovv@gmail.com
ORCID iD: 0009-0000-2712-1118
SPIN-code: 1038-0496

student

Russian Federation, Tver

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