Experience in the use of the CYFRA 21-1 tumor marker in outpatient practice

The aim of the study was to determine the significance of the tumor marker CYFRA 21-1 in the diagnosis of cancer in patients (n=27) with small focal changes in the lungs. The analysis of its level in blood serum in two groups was carried out: group 1 – primary patients (n=20, without MN, age 57±3.9 years); group 2 – patients with existing MNs (n=7, age 63±5.7 years). In both groups, according to the results of multispiral computed tomography, a single lesion in the lung parenchyma up to 1 cm was diagnosed. Determining the level of the CYFRA 21-1 tumor marker in patients with an existing malignant neoplasm is a promising method in the diagnosis of a new malignant neoplasm in the presence of a focal change in the lung parenchyma without clinically significant symptoms. In patients without cancer, in the presence of focal changes in the lungs, the determination of the level of the CYFRA 21-1 tumor marker may also be promising in the diagnosis of cancer without clinical symptoms of cancer of any localization.