Churg-Strauss syndrome in neurological practice
- Authors: Polkhovsky A.A.1
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Affiliations:
- Medical Center for Premorbid and Emergency Conditions of the P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
- Issue: Vol 344, No 8 (2023)
- Pages: 37-46
- Section: Treatment and prophylactic issues
- URL: https://journals.eco-vector.com/0026-9050/article/view/631384
- DOI: https://doi.org/10.52424/00269050_2023_344_8_37
- ID: 631384
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Abstract
Eosinophilic granulomatosis with polyangiitis of small and medium vessels (Churg–Strauss syndrome) is a rare systemic vasculitis with a unique feature: antineutrophil cytoplasmic autoantibodies and eosinophilic inflammation are involved in its pathogenesis. Despite the fact that the damage to the nervous system in this disease is in second place in frequency after asthmatic disorders, the diagnosis of the syndrome in neurological practice is very difficult. An analysis of the available literature data on the etiology, pathogenesis, clinical picture, differential diagnosis, and treatment of this pathology is presented. We present our own observation demonstrating the difficulties of neurological diagnosis of Churg–Strauss syndrome and shows that the correct interpretation of neurological symptoms at the initial stage of the disease is a necessary condition for the timely prescription of treatment, on which the patient’s life depends.
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About the authors
A. A. Polkhovsky
Medical Center for Premorbid and Emergency Conditions of the P.V.Mandryka Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Author for correspondence.
Email: neurosan@mail.ru
заслуженный врач РФ, кандидат медицинских наук, полковник медицинской службы в отставке
Russian Federation, MoscowReferences
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Fig. 1. MRI of the sinuses: a) maxillary sinuses - liquid foamy content; b) main sinus - liquid content
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Fig. 2. Retinal livedo on the skin
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Fig. 3. Muscle atrophy of the right hand: a) dorsal surface; b) palmar surface.
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Fig. 4. Muscle atrophy of the left hand: a) dorsal surface; b) palmar surface; c) palmar and ulnar surfaces
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).