Modern view of emerging and new viral infections
- Authors: Moskalev A.V.1, Gumilevsky B.Y.1, Volkov I.I.1
-
Affiliations:
- The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation
- Issue: Vol 345, No 7 (2024)
- Pages: 55-64
- Section: Epidemiology and infectious diseases
- URL: https://journals.eco-vector.com/0026-9050/article/view/636179
- DOI: https://doi.org/10.52424/00269050_2024_345_7_55
- ID: 636179
Cite item
Abstract
The characteristics of emerging and new viral infections are presented. The epidemiological features of infections, such as measles and smallpox, and their causative agents, are examined from a modern perspective. The emergence of new types of viruses is associated with variants of their interspecies transmission and features of interaction with intermediate and definitive hosts. The peculiarities of life of modern humans facilitate the spread of viruses and the emergence of new infections with the emergence of a new dominant intermediate host. Changes in the human genome and immune homeostasis have contributed to increased susceptibility to viral agents. The processes of recombination of viruses contribute to the emergence of new species. It is assumed that animal vaccination options may be promising to control the spread of viral infections, since they are the primary hosts of many viruses.
Keywords
Full Text

About the authors
A. V. Moskalev
The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation
Author for correspondence.
Email: vmeda-na@mil.ru
заслуженный работник высшей школы РФ, профессор, полковник медицинской службы в отставке
Russian Federation, St. PetersburgB. Yu. Gumilevsky
The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation
Email: vmeda-na@mil.ru
профессор
Russian Federation, St. PetersburgI. I. Volkov
The S.M.Kirov Military Medical Academy of the Ministry of Defense of the Russian Federation
Email: vmeda-na@mil.ru
доцент, полковник медицинской службы запаса
Russian Federation, St. PetersburgReferences
- Адищева О.С., Малхазова С.М., Орлов Д.С. Распространение лихорадки Западного Нила в России // Вестн. Москов. ун-та. Серия 5. География. – 2016. – № 4. – С. 48–54.
- Львов Д.К. Грипп и другие новые и возвращающиеся инфекции Северной Евразии: глобальные последствия // Федеральный справочник. Здравоохранение России. – М.: Президент, 2010. – Т. 11. – С. 209–220.
- Малеев В.В. Проблемы инфекционной патологии на современном этапе // Инфекц. болезни. – 2015. – Т. 13, № 2. – С. 5–9.
- Малова И.А., Баранова И.П. Метапневмовирусная и бокавирусная инфекция у госпитализированных больных в эпидсезоны 2011–2014 гг. // Медицинские науки. Клиническая медицина. 2015. Т. 34, № 2. С. 81–92.
- Малхазова С.М., Миронова В.А. Проблемы новых и возвращающихся инфекций: задачи медико-географического изучения // Вестн. Московского ун-та. Сер. География, Геоэкология. – 2017. – № 1. – С. 21–31.
- Медико-географический атлас России «Природноочаговые болезни» / Под ред. С.М.Малхазовой. – М.: МГУ, 2015. – 208 с.
- Титенко А.М. Санитарная охрана территории от завоза и распространения особо опасных вирусных инфекций (теоретическое и экспериментальное исследование): Автореф. дис. ...… д-ра биол. наук. – Иркутск, 2005. – 55 с.
- Шкарин В.В., Ковалишена В.В., Чанышева Р.Ф. и др. Клинико-эпидемиологические особенности новых полиэтиологичных вирусных инфекций // Эпидемиол. и вакцинопрофил. – 2018. – Т. 17, № 4. – С. 4–12.
- Ahmad L., Mostowy S., Sancho-Shimizu S. Autophagy-virus interplay: from cell biology to human disease // Front. Cell Dev. Biol. – 2018. – Vol. 19. – Р. 155.
- Burrell C., Howard C., Murphy F. Fenner and white’s medical virology, – 5th ed., San Diego, CA: Academic Press, 2016. – 454 p.
- Diner B.A., Lum K.K., Javitt A. et al. Interactions of the antiviral factor interferon gamma-inducible protein 16. NIFI16. Mediate immune signaling and Herpes simplex Virus-1 immunosuppression // Mol Cell Proteomics. – 2015. – Vol. 14, N 9. – P. 2341–2356.
- Domingo E, Perales C. Quasispecies and virus // Eur Biophys J. – 2018. – Vol. 4, N 47. – P. 443–457.
- Garcia-Sastre A. Ten strategies of interferon evasion by viruses // Cell Host Microbe. – 2017. – Vol. 22. – P. 176–184.
- Griffin D.E. The immune response in measles: virus control, clearance and protective immunity // Viruses. – 2016. – Vol. 10, N 8. – P. 282–291.
- Guo Y.J., Pan W.W., Liu S.B. ERK/MAPK signaling pathway and tumorigenesis // Experim. and therapeutic medicine. – 2020. – Vol. 19, N 3. – P. 1997–2007.
- Horie M. The biological significance of bornavirus-derived genes in mammals // Curr Opin Virol. – 2017. – Vol. 25. – P. 1–6.
- Katze M.G., Korth M.J., Law G.L. et al. Viral pathogenesis: from basics to systems biology. – 2016. – San Diego, CA: Academic Press. – 422 p.
- Krupovic M, Koonin E.V. Multiple origins of viral capsid proteins from cellular ancestors // Proc Natl Acad Sci USA. – 2017. – Vol. 12, N 114. – P. 2401–2410.
- Lee S., Liu H., Wilen C.B. et al. A secreted viral nonstructural protein deters intestinal norovirus pathogenesis // Cell Host Microbe. 2019. – Vol. 25. – P. 179–187.
- Mok Y.K., Swaminathan K., Zeeshan N. Engineering of serine protease for improved thermostability and catalytic activity using rational design // Int J Biol Macromol. – 2019. – Vol. 126. – P. 229–237.
- Parrish N.F., Tomonaga K. Endogenized viral sequences in mammals // Curr Opin Microbiol. – 2016. – Vol. 31. – P. 176–183.
- Stoye J.P. Studies of endogenous retroviruses reveal a continuing evolutionary saga // Nat Rev Microbiol. – 2012. – Vol 6, N. 10. – P. 395–406.
- Thapa R.J., Ingram J.P., Ragan K.B. et al. DAI senses influenza A virus genomic RNA and activates RIPK3-dependent cell death // Cell Host Microbe. – 2016. – Vol 20, N 5. – P. 674–681.
Supplementary files
