Sexual rehabilitation of patients after nerve-sparing radical prostatectomy.

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access

Abstract

The study included 68 patients who underwent nerve-sparing radical prostatectomy for localized prostate cancer and who had normal preoperative parameters of erectile function. Patients were divided into 2 groups, one of which was administered Tadalafil daily in a dose of 5 mg, the other group took a placebo. The results were assessed using the IIEF, EPIC, QoL questionnaires. For an objective analysis of pathophysiological changes, electroneuromyography was used. The early daily use of 5 mg Tadalafil (Cialis) in the postoperative period in patients undergoing nerve-sparing radical prostatectomy, contributes to the restoration of sexual function by improving the erection and maintaining the size of the penis. This circumstance, together with a simultaneous positive effect on the restoration of urinary retention, significantly improves the quality of life in this group of patients

Full Text

Restricted Access

References

  1. Гвасалия Б.Р., Щеплев П.А. Сексуальная функция у пациентов после реконструктивной уретропластики // Андрология и генитальная хирургия. - 2011. - № 2. - С. 95-96.
  2. Матвеев Б.В. Клиническая онкоурология. - М.: АБВ-пресс, 2011. - 934 с.
  3. Ситников Н.В., Билык Н.Л., Кочетов А.Г. и др. Электронейромиография в диагностике эректильной дисфункции после радикальной простатэктомии // Материалы II конгресса Российского общества онкоурологов. - 2007. - С. 52-53.
  4. Barazani Y., Stahl P.J., Nagler H.M. et al. Is there a rationale for penile rehabilitation following radical prostatectomy? // Am. J. Mens Health. - 2015. - Vol. 9, N 1. - P. 35-43.
  5. Benson C.R., Serefoglu E.C., Hellstrom W.J. Sexual dysfunction following radical prostatectomy // J. Androl. - 2012. - Vol. 33, N 6. - P. 1143-1154.
  6. Chung E., Brock G. Sexual rehabilitation and cancer survivorship: a state of art review of current literature and management strategies in male sexual dysfunction among prostate cancer survivors // J. Sex. Med. - 2013. - Vol. 10, N 1. - Р. 102-111.
  7. Gandaglia G., Gallina A., Suardi N. et al. Preoperative erectile function is the only predictor of the use of a high number of phosphodiesterase type-5 inhibitors after bilateral nerve-sparing radical prostatectomy // Int. J. Impot. Res. - 2014. - Vol. 26, N 6. - P. 201-204.
  8. Hyun J.S. Prostate cancer and sexual function // World J. Mens Health. - 2012. - Vol. 30, N 2. - P. 99-107.
  9. Lee T., Fenstermaker M., Taksler G.B. et al. Long-term satisfaction after open radical prostatectomy // Urology. - 2015. - Vol. 85, N 5. - Р. 1130-1136.
  10. Levinson A.W., Lavery H.J., Ward N.T. et al. Is a return to baseline sexual function possible? An analysis of sexual function outcomes following laparoscopic radical prostatectomy // World J. Urol. - 2011. - Vol. 29, N 1. - Р. 29-34.
  11. Megas G., Papadopoulos G., Stathouros G.et al. Comparison of efficacy and satisfaction profile, between penile prosthesis implantation and oral PDE5 inhibitor tadalafil therapy, in men with nerve-sparing radical prostatectomy erectile dysfunction // BJU Int. - 2013. - Vol. 112, N 2. - Р. 169-176.
  12. Menard J., Tremeaux J.C., Faix A. et al. Erectile function and sexual satisfaction before and after penile prosthesis implantation in radical prostatectomy patients: a comparison with patients with vasculogenic erectile dysfunction // J. Sex. Med. - 2011. - Vol. 8, N 12. - Р. 3479-3486.
  13. Montesi L., Quaresima L., Tiroli M. et al. Improvement of lower urinary tract symptoms and sexual activity after open simple prostatectomy: prospective analysis of 50 cases // Arch. Ital. Urol. Androl. - 2014. - Vol. 86, N 4. - Р. 353-355.
  14. Montorsi F., Brock G., Stolzenburg J.U. et al. Effects of tadalafil treatment on erectile function recovery following bilateral nerve-sparing radical prostatectomy: a randomised placebo-controlled study (REACTT) // Eur. Urol. - 2014. - Vol. 65, N 3. - Р. 587-596.
  15. Mulhall J.P., Bivalacqua T.J., Becher E.F. Standard operating procedure for the preservation of erectile function outcomes after radical prostatectomy // J. Sex. Med. - 2013. - Vol. 10, N 1. - Р. 195-203.
  16. Namiki S., Ishidoya S., Nakagawa H. et al. The relationships between preoperative sexual desire and quality of life following radical prostatectomy: a 5-year follow-up study // J. Sex. Med. - 2012. - Vol. 9, N 9. - Р. 2448-2456.
  17. Namiki S., Kaiho Y., Mitsuzuka K. et al. Long-term quality of life after radical prostatectomy: 8-year longitudinal study in Japan // Int. J. Urol. - 2014. - Vol.21, N 12. - Р. 1220-1226.
  18. Patel H.R., Ilo D., Shah N. et al. Effect softadalafil treatment after bilateral nerve-sparing radical prostatectomy: quality of life, psychosocial outcomes, and treatment satisfaction results from a randomized, placebo-controlled phase IV study // BMC Urol. - 2015. - Vol. 15, N 1. - 31 р.
  19. Sivarajan G., Prabhu V., Taksler G.B. et al. Ten-year outcomes of sexual function after radical prostatectomy: results of a prospective longitudinal study // Eur. Urol. - 2014. - Vol. 65, N 1. - Р. 58-65.
  20. Stember D.S., Nelson C.J., Mulhall J.P. Preoperative erectile function is an independent predictor for decision to spare cavernous nerves during radical prostatectomy // J. Sex. Med. - 2013. - Vol. 10, N 8. - Р. 2101-2107.
  21. Tran S.N., Wirth G.J., Mayor G. et al. Prospective evaluation of early postoperative male and female sexual function after radical prostatectomy with erectile nerves preservation // Int. J. Impot. Res. - 2015. - Vol. 27, N 2. - Р. 69-74.
  22. Wittmann D., Carolan M., Given B. et al. What couples say about their recovery of sexual intimacy after prostatectomy: toward the development of a conceptual model of couples’sexual recovery after surgery for prostate cancer // J. Sex. Med. - 2015. - Vol. 12, N 2. - Р. 494-504.
  23. Wronski S. The new horizons of pharmacotherapy. Unexpected pharmacological actions and a new therapeutic strategy of phosphodiesterase-5 inhibitors // Cent. European J. Urol. - 2014. - N 67. - Р. 314-318.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2017 Esipov A.V., Kochetov A.G., Ivanov A.O., Gvasaliya B.R., Kostin A.A., Shidlovskii I.P., Karabach I.V., Ponomarev V.K., Esipov A.S.



СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: № 01975 от 30.12.1992.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies