Sexual rehabilitation of patients after nerve-sparing radical prostatectomy.

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The study included 68 patients who underwent nerve-sparing radical prostatectomy for localized prostate cancer and who had normal preoperative parameters of erectile function. Patients were divided into 2 groups, one of which was administered Tadalafil daily in a dose of 5 mg, the other group took a placebo. The results were assessed using the IIEF, EPIC, QoL questionnaires. For an objective analysis of pathophysiological changes, electroneuromyography was used. The early daily use of 5 mg Tadalafil (Cialis) in the postoperative period in patients undergoing nerve-sparing radical prostatectomy, contributes to the restoration of sexual function by improving the erection and maintaining the size of the penis. This circumstance, together with a simultaneous positive effect on the restoration of urinary retention, significantly improves the quality of life in this group of patients

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  1. Гвасалия Б.Р., Щеплев П.А. Сексуальная функция у пациентов после реконструктивной уретропластики // Андрология и генитальная хирургия. - 2011. - № 2. - С. 95-96.
  2. Матвеев Б.В. Клиническая онкоурология. - М.: АБВ-пресс, 2011. - 934 с.
  3. Ситников Н.В., Билык Н.Л., Кочетов А.Г. и др. Электронейромиография в диагностике эректильной дисфункции после радикальной простатэктомии // Материалы II конгресса Российского общества онкоурологов. - 2007. - С. 52-53.
  4. Barazani Y., Stahl P.J., Nagler H.M. et al. Is there a rationale for penile rehabilitation following radical prostatectomy? // Am. J. Mens Health. - 2015. - Vol. 9, N 1. - P. 35-43.
  5. Benson C.R., Serefoglu E.C., Hellstrom W.J. Sexual dysfunction following radical prostatectomy // J. Androl. - 2012. - Vol. 33, N 6. - P. 1143-1154.
  6. Chung E., Brock G. Sexual rehabilitation and cancer survivorship: a state of art review of current literature and management strategies in male sexual dysfunction among prostate cancer survivors // J. Sex. Med. - 2013. - Vol. 10, N 1. - Р. 102-111.
  7. Gandaglia G., Gallina A., Suardi N. et al. Preoperative erectile function is the only predictor of the use of a high number of phosphodiesterase type-5 inhibitors after bilateral nerve-sparing radical prostatectomy // Int. J. Impot. Res. - 2014. - Vol. 26, N 6. - P. 201-204.
  8. Hyun J.S. Prostate cancer and sexual function // World J. Mens Health. - 2012. - Vol. 30, N 2. - P. 99-107.
  9. Lee T., Fenstermaker M., Taksler G.B. et al. Long-term satisfaction after open radical prostatectomy // Urology. - 2015. - Vol. 85, N 5. - Р. 1130-1136.
  10. Levinson A.W., Lavery H.J., Ward N.T. et al. Is a return to baseline sexual function possible? An analysis of sexual function outcomes following laparoscopic radical prostatectomy // World J. Urol. - 2011. - Vol. 29, N 1. - Р. 29-34.
  11. Megas G., Papadopoulos G., Stathouros al. Comparison of efficacy and satisfaction profile, between penile prosthesis implantation and oral PDE5 inhibitor tadalafil therapy, in men with nerve-sparing radical prostatectomy erectile dysfunction // BJU Int. - 2013. - Vol. 112, N 2. - Р. 169-176.
  12. Menard J., Tremeaux J.C., Faix A. et al. Erectile function and sexual satisfaction before and after penile prosthesis implantation in radical prostatectomy patients: a comparison with patients with vasculogenic erectile dysfunction // J. Sex. Med. - 2011. - Vol. 8, N 12. - Р. 3479-3486.
  13. Montesi L., Quaresima L., Tiroli M. et al. Improvement of lower urinary tract symptoms and sexual activity after open simple prostatectomy: prospective analysis of 50 cases // Arch. Ital. Urol. Androl. - 2014. - Vol. 86, N 4. - Р. 353-355.
  14. Montorsi F., Brock G., Stolzenburg J.U. et al. Effects of tadalafil treatment on erectile function recovery following bilateral nerve-sparing radical prostatectomy: a randomised placebo-controlled study (REACTT) // Eur. Urol. - 2014. - Vol. 65, N 3. - Р. 587-596.
  15. Mulhall J.P., Bivalacqua T.J., Becher E.F. Standard operating procedure for the preservation of erectile function outcomes after radical prostatectomy // J. Sex. Med. - 2013. - Vol. 10, N 1. - Р. 195-203.
  16. Namiki S., Ishidoya S., Nakagawa H. et al. The relationships between preoperative sexual desire and quality of life following radical prostatectomy: a 5-year follow-up study // J. Sex. Med. - 2012. - Vol. 9, N 9. - Р. 2448-2456.
  17. Namiki S., Kaiho Y., Mitsuzuka K. et al. Long-term quality of life after radical prostatectomy: 8-year longitudinal study in Japan // Int. J. Urol. - 2014. - Vol.21, N 12. - Р. 1220-1226.
  18. Patel H.R., Ilo D., Shah N. et al. Effect softadalafil treatment after bilateral nerve-sparing radical prostatectomy: quality of life, psychosocial outcomes, and treatment satisfaction results from a randomized, placebo-controlled phase IV study // BMC Urol. - 2015. - Vol. 15, N 1. - 31 р.
  19. Sivarajan G., Prabhu V., Taksler G.B. et al. Ten-year outcomes of sexual function after radical prostatectomy: results of a prospective longitudinal study // Eur. Urol. - 2014. - Vol. 65, N 1. - Р. 58-65.
  20. Stember D.S., Nelson C.J., Mulhall J.P. Preoperative erectile function is an independent predictor for decision to spare cavernous nerves during radical prostatectomy // J. Sex. Med. - 2013. - Vol. 10, N 8. - Р. 2101-2107.
  21. Tran S.N., Wirth G.J., Mayor G. et al. Prospective evaluation of early postoperative male and female sexual function after radical prostatectomy with erectile nerves preservation // Int. J. Impot. Res. - 2015. - Vol. 27, N 2. - Р. 69-74.
  22. Wittmann D., Carolan M., Given B. et al. What couples say about their recovery of sexual intimacy after prostatectomy: toward the development of a conceptual model of couples’sexual recovery after surgery for prostate cancer // J. Sex. Med. - 2015. - Vol. 12, N 2. - Р. 494-504.
  23. Wronski S. The new horizons of pharmacotherapy. Unexpected pharmacological actions and a new therapeutic strategy of phosphodiesterase-5 inhibitors // Cent. European J. Urol. - 2014. - N 67. - Р. 314-318.

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