The innate immunity and activation of the atherogenesis


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Abstract

The worldwide recognized founder of the scientific concept of atherogenesis is the Russian scientist, representative of the Military-medical academy N.N.Anichkov (1885-1964), who was born in Saint-Petersburg. The authors analysed current information on the complex of formation atherogenesis mechanisms, based on interaction of different ligands with pathogen recognition receptor of different cells of congenital immune, including toll-like receptors and scavenger receptor. The specific nature of the activation of innate immunity receptors, cross-regulation of toll-like and scavenger receptors by endogenous ligands determines asymptomatic nature of the atherogenesis as the result of the sterile inflammation.

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Copyright (c) 2016 Tsygan V.N., Bubnov V.A., Tsygan N.V., Zinovev E.V., Ivchenko E.V., Anichkov N.M., Mirolyubov A.V., Dergunov A.V., Kazachenko A.I.


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: № 01975 от 30.12.1992.

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