Promising technologies of packed red blood cells production and storage

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access


The current article is dedicated to promising technologies of packed red blood cells production and storage. The following new technical approaches are presented: (1) erythrocytes storage in strict anaerobic argon-hydrogen environment, (2) lyophilization of erythrocyte suspension by its atomization in nitrogen gas, (3) lyophilization of erythrocytes by directional freezing under the influence of radio frequency radiation, (4) automated pharming of antigen free packed red blood cells from progenitor cell directly at the battlefield.

Full Text

Restricted Access


  1. Arav A. Freeze Drying Red Blood Cells: Development of Novel Technologies // American College of Cryosurgery Conference. January 2nd-7th, 2013. Miami, Florida, USA. PDF. URL: 2013/accryo2013_proceedings.pdf (дата обращения: 03.10.2013).
  2. Arav A., Natan D. Freeze Drying of Red Blood Cells: The Use of Directional Freezing and a New Radio Frequency Lyophilization Device // Biopreserv Biobank. - 2012. - Vol. 10, N 4. - P. 386-394. Abstr. URL: http://online. 0021?journalCode=bio (дата обращения: 03.10.2013).
  3. Blood Pharming // The Official Web Site of the DARPA. URL: Our_Work/DSO/Programs/Blood_Pharming.aspx (дата обращения: 03.10.2013).
  4. Blood Pharming. Program Images. Image // The Official Web Site of the DARPA. URL: «Военно-медицинский журнал», 10’2013_ Our_Work/DSO/Programs/Blood_Pharming/ Blood20Pharming_image1.jpg%5B1%5D.jpg (дата обращения: 03.10.2013).
  5. McLean M., Han X.-Y., Higgins A.Z. Spray Drying for Preservation of Erythrocytes: Effect of Atomization on Hemolysis // Biopreserv Biobank. - 2013. - Vol. 10, N 2. - P. 122-123. Abstr. URL: bio.2012.0060 (дата обращения: 03.10.2013).
  6. Proposed Standards for Blood Banks and Transfusion Services, 29th edition, 29 April 2013 // The Official Web Site of the American Association of Blood Banks (AABB). 124 p. PDF. URL: (дата обращения: 03.10.2013).
  7. Spray Drying for Long Term Storage of Red Blood Cells / Meehe Kim, Mary McLean, John Simeles, Dr. Adam Higgins (Sponsor) // Oregon State University. PDF. uRL: http:// /fles/studentprojects/2011/Expo_Lite_Posters/ ExpoLitePoster_Kim_McLean_Simeles.pdf (дата обращения: 03.10.2013).
  8. The Armed Services Blood Program. April 2013 // The Official Web Site of the US Armed Services Blood Program. 15 p. PDF. URL: /PressKit_04_01_13.pdf (дата обращения: 03.10.2013).
  9. Uri M., Damari Y. Device for directional cooling of biological matter. United States Patent 8196416. Publication Date: 06 December 2012 // 12 p. PDF. URL: http:// (дата обращения: 03.10.2013).
  10. Yoshida T., Shevkoplyas S.S. Anaerobic storage of red blood cells // Blood Transfus. -2010. - Vol. 8, N 4. - P. 220-236. PDF. URL: 20Transfusion_022-10_pre-publishing.pdf (дата обращения: 03.10.2013).

Copyright (c) 2013 Eco-Vector

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies