A case of tolerance to neprilysin inhibitors as a new factor in the cumulation of mortality in patients with chronic heart failure
- Authors: Tsygvintsev A.A1, Lishchuk A.N1, Storozhilov V.A1
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Affiliations:
- the 3rd A.A.Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
- Issue: Vol 341, No 9 (2020)
- Pages: 67-69
- Section: Articles
- URL: https://journals.eco-vector.com/0026-9050/article/view/82440
- DOI: https://doi.org/10.17816/RMMJ82440
- ID: 82440
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Abstract
Based on four years of clinical experience with saсubitrile/valsartan use, the authors faced the problem of cumulation of mortality in patients. Long-term clinical observation of a comorbid patient who received adequate therapy of high functional class chronic heart failure, which ended in death, is presented. The concept of management of such patients used by us from the perspective of evidence-based medicine is considered.
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About the authors
A. A Tsygvintsev
the 3rd A.A.Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation
Email: tsygvintsev1985@gmail.com
Krasnoznamensk, Moscow region, Russia
A. N Lishchuk
the 3rd A.A.Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of the Russian FederationKrasnogorsk, Moscow region, Russia
V. A Storozhilov
the 3rd A.A.Vishnevsky Central Military Clinical Hospital of the Ministry of Defense of the Russian FederationKrasnoznamensk, Moscow region, Russia
References
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- Руководство по кардиологии в четырех томах. Т. 4: Заболевания сердечно - сосудистой системы / Под ред. Е.И.Чазова. - М.: Практика, 2014. - 976 с.
- Chang H.Y., Feng A.N., Fong M.C. et al. Sacubitril/valsartan in heart failure with reduced ejection fraction patients: Real world experience on advanced chronic kidney disease, hypotension, and dose escalation // J. Cardiol. - 2019. - Vol. 74, N 4. - P. 372-380.
- Jhund P., Claggett B., Packer M. et al. Independence of the blood pressure lowering effect and efficacy of the angiotensin receptor neprilysin inhibitor, LCZ696, in patients with heart failure with preserved ejection fraction: an analysis of the PARAMOUNT trial // Eur. J. Heart Fail. - 2014. - Vol. 16, N 6. - P. 671-677.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).