A case of long - term extracorporeal membrane oxygenation in the treatment of acute respiratory distress syndrome in a patient with COVID-19


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Abstract

The most common clinical manifestation of COVID-19 is a bilateral lung disease, with acute respiratory distress syndrome (ARDS) developing in 3-4% of cases. The experience of using extracorporeal membrane oxygenation with the ineffectiveness of mechanical ventilation in the treatment of ARDS in patients with coronavirus infection is insignificant. The article demonstrates a case of long - term (30 days) use of extracorporeal membrane oxygenation in a patient with viral total lung disease, CT-4, severe acute respiratory distress syndrome. The possibility and efficiency of the long - term application of the method are presented. Anticoagulant therapy using low molecular weight heparin (enoxaparin) is adequate, reduces the risk of bleeding, determines the duration and effectiveness of using a membrane oxygenator, and reduces the likelihood of thrombosis of the extracorporeal circuit, and preserves its oxygenating function.

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About the authors

E. V Kryukov

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Email: evgeniy.md@mail.ru
Moscow, Russia

V. A Chernetsov

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Moscow, Russia

A. E Shestopalov

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Moscow, Russia

V. V Stets

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Moscow, Russia

A. G Zhuravlev

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Moscow, Russia

V. V Morgachev

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Moscow, Russia

D. S Meshcheryakov

The N.N.Burdenko Main Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Moscow, Russia

References

  1. Abrams D., Ferguson N., Brochard L. et al. ECMO for ARDS: from salvage to standard of care? // The Lancet Respiratory Medicine. - 2019. - Vol. 7, N 2. - P. 108-110.
  2. Extracorporeal Life Support Organization, General Guidelines for all ECLS Cases, 2019.
  3. https://sccm.org/SurvivingSepsisCampaign /Guidelines/COVID-19
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  5. https://www.elso.org/Resources/Guide lines.aspx
  6. Li M., Gu S-Ch., Wu X-C. et al. Extracorporeal membrane oxygenation support in 2019 novel coronavirus disease: indications, timing, and implementation // Chinese Med. J. - 2020. - Vol. 133, N 9. - P. 1115-1117.
  7. Ramanathan K., Antognini D., Combes A. et al. Planning and provision of ECMO services for severe ARDS during the COVID-19 pandemic and other outbreaks of emerging infectious diseases // Lancet Respir Med. - 2020. - Vol. 8, Iss. 5. - P. 518-526.

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Copyright (c) 2021 Kryukov E.V., Chernetsov V.A., Shestopalov A.E., Stets V.V., Zhuravlev A.G., Morgachev V.V., Meshcheryakov D.S.



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