Syndromic pathological processes in toxic and radiation injuries: assess their mechanisms and search for pharmacological correction approaches

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Abstract

A comparison of the syndromes of somatic and neurological diseases with pathological conditions arising from toxic and radiation injuries and the reproduction of which is excluded when studying the effectiveness of medical protective equipment has been carried out. Considering the pathogenetic commonality of syndromic processes, the possibility of using the results of clinical trials of drugs to create medical remedies and adjusting experimental data regarding the prognosis of effective and safe doses of drugs is shown. Formation of the concept of syndromic conditions will expand the possibilities for assessing the effectiveness of medications concerning the means of pathogenetic and symptomatic therapy of toxic and radiation injuries.

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About the authors

S. V Chepur

The State Research and Testing Institute for Military Medicine of the Ministry of Defense of the Russian Federation

Email: gniiivm_15@mil.ru
St. Petersburg, Russia

M. A Yudin

The State Research and Testing Institute for Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, Russia

I. S Drachev

The State Research and Testing Institute for Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, Russia

M. A Tyunin

The State Research and Testing Institute for Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, Russia

V. A Basharin

The S.M.Kirov Military Medical Academy

St. Petersburg, Russia

E. V Pronina

the State Research and Testing Institute of Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, pos. Strelna, Russia

E. V Morozov

the State Research and Testing Institute of Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, pos. Strelna, Russia

V. A Stepanov

the State Research and Testing Institute of Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, pos. Strelna, Russia

A. V Mosin

the State Research and Testing Institute of Military Medicine of the Ministry of Defense of the Russian Federation

St. Petersburg, pos. Strelna, Russia

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