Mathematical prediction of aspiration doses of microbial aerosols

The article discusses two methodological approaches to predicting aspiration doses of microbial aerosols - deterministic and probabilistic. It is shown that at low concentrations of microbial aerosol, the deterministic method of solving the problem gives rough and overestimated estimates of the aspiration doses of microorganisms. Under similar conditions, the application of the probabilistic approach demonstrates a slower dynamic of the accumulation of microbes in the respiratory tract, associated with the uneven spatio - temporal distribution of microbial aerosol particles in the air and the identity of the human respiratory cycles. This is relevant for predicting the aerogenic infection of recipients by microorganisms having low infectious doses (single cells), as well as for the process of indicating low concentrations of microbial aerosol in space - time coordinates.

respiratory tract, infection, microbial aerosols, aspiration doses, prediction, probabilistic model