Clinical observation of a comorbid cardiac patient with a deficiency of VIII, IX blood clotting factors

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The treatment of comorbid patients with heart failure is traditionally associated with a high probability of polypharmacy and the realization of undesirable drug effects. The choice of management tactics for patients who have recently undergone cardiac surgery with a high risk of both thrombotic and hemorrhagic complications against the background of concomitant hematological pathology seems to be especially controversial. This paper presents the results of long-term clinical observation of a patient with a deficiency of VIII, IX factors of blood coagulation, cardiorenal anemic syndrome, performed by implantation of a pacemaker and stenting of the coronary artery. The tactics of managing such patients from the standpoint of evidence-based medicine are discussed.

作者简介

A. Tsygvintsev

Branch No. 4 of the A.A.Vishnevsky 3 Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation

编辑信件的主要联系方式.
Email: tsygvintsev1985@gmail.com

кандидат медицинских наук, капитан медицинской службы

俄罗斯联邦, Krasnoznamensk, Moscow region

N. Gulyaev

The A.A. Vishnevsky 3rd Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Email: tsygvintsev1985@gmail.com

доктор медицинских наук, полковник медицинской службы

俄罗斯联邦, Krasnogorsk, Moscow Region

A. Lishchuk

The A.A. Vishnevsky 3rd Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Email: tsygvintsev1985@gmail.com

заслуженный врач РФ, профессор, полковник медицинской службы запаса

俄罗斯联邦, Krasnogorsk, Moscow Region

P. Shakhnovich

Central Clinical Hospital with a polyclinic of the Administrative Department of the President of the Russian Federation

Email: p_shakhnovich@mail.ru

доктор медицинских наук, полковник медицинской службы запаса

俄罗斯联邦, Moscow

参考

  1. Ватутин Н.Т., Тарадин Г.Г., Канишева И.В., Венжега В.В. Анемия и железодефицит у больных с хронической сердечной недостаточностью // Кардиология. – 2019. – Т. 59, № 4. – С. 4–20.
  2. Галявич А.С., Стекольщикова Н.Ю., Касимова Р.А., Мухамедназарова Ф.И. Инфаркт миокарда и гемофилия // Рос. кардиол. журн. – 2016. – № 4. – С. 117–119.
  3. Мороз Е.В., Каратеев А.Е., Крюков Е.В., Чернецов В.А. Желудочно-кишечные кровотечения при использовании новых пероральных антикоагулянтов: эпидемиология, факторы риска, лечение и профилактика // Науч.-практ. ревматол. – 2017. – Т. 55, № 6. – С. 675–684.
  4. Anand I., Gupta P. Anemia and Iron Deficiency in Heart Failure: Current Concepts and Emerging Therapies // Circulation. – 2018. – Vol. 138, N 1. – P. 80–98.
  5. Bello N.A., Lewis E.F., Desai A.S et al. Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease // Eur. J. Heart Fail. – 2015. – Vol. 17, N 11. – P. 1201–1207.
  6. Grote Beverborg N., van Veldhuisen D.J., van der Meer P. Anemia in Heart Failure // JACC: Heart Failure. – 2018. – Vol. 6, N 3. – P. 201–208.
  7. Van der Wal H., Comin-Colet J., Klip I. et al. Vitamin B12 and folate deficiency in chronic heart failure // Heart. – 2015. – Vol. 101, N 4. – P. 302–310.

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