Clinical observation of a comorbid cardiac patient with a deficiency of VIII, IX blood clotting factors

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Abstract

The treatment of comorbid patients with heart failure is traditionally associated with a high probability of polypharmacy and the realization of undesirable drug effects. The choice of management tactics for patients who have recently undergone cardiac surgery with a high risk of both thrombotic and hemorrhagic complications against the background of concomitant hematological pathology seems to be especially controversial. This paper presents the results of long-term clinical observation of a patient with a deficiency of VIII, IX factors of blood coagulation, cardiorenal anemic syndrome, performed by implantation of a pacemaker and stenting of the coronary artery. The tactics of managing such patients from the standpoint of evidence-based medicine are discussed.

About the authors

A. A. Tsygvintsev

Branch No. 4 of the A.A.Vishnevsky 3 Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Author for correspondence.
Email: tsygvintsev1985@gmail.com

кандидат медицинских наук, капитан медицинской службы

Russian Federation, Krasnoznamensk, Moscow region

N. I. Gulyaev

The A.A. Vishnevsky 3rd Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Email: tsygvintsev1985@gmail.com

доктор медицинских наук, полковник медицинской службы

Russian Federation, Krasnogorsk, Moscow Region

A. N. Lishchuk

The A.A. Vishnevsky 3rd Central Military Clinical Hospital of the Ministry of Defense of the Russian Federation

Email: tsygvintsev1985@gmail.com

заслуженный врач РФ, профессор, полковник медицинской службы запаса

Russian Federation, Krasnogorsk, Moscow Region

P. G. Shakhnovich

Central Clinical Hospital with a polyclinic of the Administrative Department of the President of the Russian Federation

Email: p_shakhnovich@mail.ru

доктор медицинских наук, полковник медицинской службы запаса

Russian Federation, Moscow

References

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  5. Bello N.A., Lewis E.F., Desai A.S et al. Increased risk of stroke with darbepoetin alfa in anaemic heart failure patients with diabetes and chronic kidney disease // Eur. J. Heart Fail. – 2015. – Vol. 17, N 11. – P. 1201–1207.
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  7. Van der Wal H., Comin-Colet J., Klip I. et al. Vitamin B12 and folate deficiency in chronic heart failure // Heart. – 2015. – Vol. 101, N 4. – P. 302–310.

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Copyright (c) 2022 Tsygvintsev A.A., Gulyaev N.I., Lishchuk A.N., Shakhnovich P.G.



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