Dependencies of psychophysiological status, immunity and blood pressure in the crew with arterial hypertension in the Far North

A total of 54 military personnel aged 30-45 years (average 34±8.4 years) were divided into 2 groups: 1st (n=34) - specialists of surface crews with identified hypertension and asthenoneurotic disorders; Group 2 (n=20) - military with hypertension without neurotic disorders (control). In the 1st group, the presence of regulatory dysfunctions in the neuropsychological adaptation system, the supersegmental area of the autonomic nervous system, and the immune system, affecting the clinical course of hypertension, was revealed. The nature of regulatory dysfunctions is due to impaired psychological and psychophysiological status (high anxiety, depression and stress-mediated reactions), autonomic regulation (low levels of b-endorphin, sympathicotonia and autonomous stimulation), changes in the cytokine immunity pool (increased levels of pro-inflammatory and decreased anti-inflammatory cytokines ) and the functioning of the cardiovascular system (high level of average daily systolic and diastolic arterial pressure during the day and night periods).

marine medicine, neuropeptide-cytokine pool, arterial hypertension, asthenoneurotic states