Modern approaches to evaluating the effectiveness of treatment of chronic heart failure


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Abstract

The efficacy of therapy for patients with chronic heart failure, a new combination drug valsartan/sacubitrile according to the levels of biomarkers ST2 and NT-proBNP was evaluated. In all patients of the study group, valsartan/sacubitrile therapy improved the NYHA functional class, in the control group - only in 75%. The dynamics of indicators of biomarkers ST2 and NT-proBNP coincided with the improvement of the clinical status of patients against the background of therapy, and to a greater extent this trend reflects the indicator NT-proBNP.

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Copyright (c) 2019 Potekhin N.P., Fursov A.N., Kazakov S.P., Putkov S.B., Pestovskaya O.R., Lyapkova N.B., Zakharova E.G., Makeeva T.G., Vereshchagina A.V.


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