Clinical biochemical and toxicological evaluation of Silybum marianum

A dosage form with Silybum marianum oil meal as a mean for correcting liver condition is developed. To evaluate the effectiveness and tolerability profile was performed a study involving 40 volunteers with destructive changes of the liver. On completing the study, it was revealed that the given medical product has the following effects: hepatoprotective activity of the developed formula, reduction of the risk of bile duct obstruction, prolonged beneficial effect on the functional status of hepatocytes. The medical product did not cause toxic side effects and showed a good tolerability profile.

functional disorders of the liver, Silybum marianum oil meal, hepatoprotective effect