Risk factors for gastrointestinal bleeding in patients with acute coronary syndrome

The article gives an idea of the main risk factors that are predictors of gastrointestinal bleeding in the treatment of patients using double and triple antiplatelet therapy regimens for the acute coronary syndrome. 65 men with the acute coronary syndrome were examined. Most patients have a high prevalence of risk factors for bleeding (over 65 years of age - 80%, arterial hypertension - 49%, renal dysfunction - 57%, anamnesis of the complicated course of peptic ulcer disease - 21.5%) and the need for prophylactic administration of secretolytics. Many patients who underwent percutaneous coronary intervention due to acute coronary syndrome, due to the high risk of gastrointestinal bleeding, should take a long - term therapy with proton pump blockers (omeprazole, rabeprazole). The intake of rabeprazole is preferable for this category of patients due to the smaller number of dyspeptic complaints, a long antisecretory effect, and the optimal cost of the drug.

gastrointestinal bleeding, coronary heart disease, proton pump inhibitors, acute coronary syndrome, percutaneous coronary intervention, rabeprazole