No 2 (2023)

Antidepressant resistance poses one of the biggest challenges to modern neuropharmacology. Here we will try to consider the problem in terms of the serotonin system. What are its features and how can they cause therapeutic resistance? In addition, special attention will be paid to serotonin receptors, whose amazing biology not only shed light on the mechanisms of depressive disorders, but also promise to provide the key to the effective therapy of the latters.

The article attempts to overview the current knowledge on the location and origin of authigenic carbonates in the ocean, which bind carbon from different sources and affect the mass balance of carbon and sulfur isotopes. Of greatest interest among marine authigenic carbonates are methane derived crusts and nodules in sediments near the cold methane seeps. By the early 2000s, a consortium of methanotrophic archaea and sulfate-reducing bacteria capable of oxidizing methane was found in anaerobic sulfate-containing ecosystems. This biogeochemical process results in a formation of a powerful microbial filter that reduces natural emission of methane, one of the main greenhouse gases.

On December 12, 2022, the Decree of the Government of the Russian Federation (No.2284) decreed the creation of the Chersky National Park named after A.V. Andreev in Magadan Oblast, one of the most famous mining regions in the world. Its area is more than 460 thousand km2 and about 10% (more than 50 thousand km2) of it is covered with “metastases” of placer gold mining. The geological “development” in the region is the most important factor in its advancement; however it also results in formation of unsightly lunar landscapes on the vast areas of the upper reaches of the Kolyma River. The development of the system of specially protected natural areas in the North-East of Russia and in particular, in Magadan Oblast is associated with the name of the famous geologist A.P.Vaskovsky.

Книга Александры Горяшко «Острова блаженных» посвящена истории российских биологических станций, расположенных на берегах Белого и Баренцева морей, от основания до современности.