Regulation of Gene Expression, or What Enables Genes to Operate

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Abstract

Genes preserve hereditary information, which is identical in all cells of the multicellular organism. Diff erent expression of genes ensures the formation of diff erent traits (for example, the formation of diff erent cell types). The mechanisms that aff ect gene expression are the subject to heavy scrutiny of research. The technological advances of the last two decades open up wide perspectives for in-depth studies of these mechanisms. In the review, we consider the reasons for the diff erent expression of the genes and the ways to measure gene activity and to determine its causes.

About the authors

A. A Maslakova

Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences

Email: maslakova@bionet.nsc.ru
Novosibirsk, Russia

V. A Dolgikh

Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences

Email: dolgikh@bionet.nsc.ru
Novosibirsk, Russia

E. V Zemlyanskaya

Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences; Novosibirsk State University

Email: ezemlyanskaya@bionet.nsc.ru
Novosibirsk, Russia; Novosibirsk, Russia

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