BRAIN-DERIVED NEUROTROPHIC FACTOR AS AN INDICATOR OF CENTRAL NERVOUS SYSTEM DISEASES


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Abstract

The paper reviews the literature on the involvement of brain-derived neurotrophic factor (BDNF) in the pathogenesis of many diseases of the central nervous system. It presents data of the studies showing a correlation between BDNF deficiency in the brain and blood tissues and neurodegenerative diseases, such as AlzheimePs, Huntington’s, Parkinson’s diseases, hypoxia, headaches and migraines, and psychoemotional disorders. It is shown that BDNF can serve as a marker for predicting the course of diseases and evaluating the efficiency of treatment.

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About the authors

Yu. V Zykova

OOO «Medicine of Computer Technologies» Medical and Diagnostic Clinic

Krasnoyarsk

L. S Evert

Federal Research Center “Krasnoyarsk Research Center, Siberian Branch, Russian Academy of Sciences

MD, Research Institute for Medical Problems of the North Krasnoyarsk

T. V Potupchik

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Email: potupchik_tatyana@mail.ru
Candidate of Medical Sciences Krasnoyarsk

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